Literature DB >> 34588214

Exploring New Approaches for Locally Advanced Gastroesophageal Adenocarcinomas: TNT, Irinotecan, and ctDNA.

Daniel V T Catenacci1.   

Abstract

The authors of a recent pilot study incorporated novel concepts including total neoadjuvant therapy with induction triplet FOLFIRINOX then chemoradiotherapy before surgery, along with ctDNA minimal residual disease analyses demonstrating both feasibility of this approach as well as confirming prognostic value of ctDNA analysis before and after surgery.See related article by Wo et al., p. 6343. ©2021 American Association for Cancer Research.

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Year:  2021        PMID: 34588214      PMCID: PMC8639623          DOI: 10.1158/1078-0432.CCR-21-2777

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN: 1078-0432            Impact factor:   13.801


  5 in total

1.  Circulating Tumor DNA Sequencing Analysis of Gastroesophageal Adenocarcinoma.

Authors:  Steven B Maron; Leah M Chase; Samantha Lomnicki; Sara Kochanny; Kelly L Moore; Smita S Joshi; Stacie Landron; Julie Johnson; Lesli A Kiedrowski; Rebecca J Nagy; Richard B Lanman; Seung Tae Kim; Jeeyun Lee; Daniel V T Catenacci
Journal:  Clin Cancer Res       Date:  2019-08-19       Impact factor: 12.531

2.  Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline.

Authors:  Manish A Shah; Erin B Kennedy; Daniel V Catenacci; Dana C Deighton; Karyn A Goodman; Narinder K Malhotra; Christopher Willett; Brendon Stiles; Prateek Sharma; Laura Tang; Bas P L Wijnhoven; Wayne L Hofstetter
Journal:  J Clin Oncol       Date:  2020-06-22       Impact factor: 44.544

3.  Evaluation of the Association of Perioperative UGT1A1 Genotype-Dosed gFOLFIRINOX With Margin-Negative Resection Rates and Pathologic Response Grades Among Patients With Locally Advanced Gastroesophageal Adenocarcinoma: A Phase 2 Clinical Trial.

Authors:  Daniel V T Catenacci; Leah Chase; Samantha Lomnicki; Theodore Karrison; Robert de Wilton Marsh; Murtuza M Rampurwala; Sunil Narula; Lindsay Alpert; Namrata Setia; Shu-Yuan Xiao; John Hart; Uzma D Siddiqui; Bryan Peterson; Kelly Moore; Kristin Kipping-Johnson; Ugne Markevicius; Barbara Gordon; Kenisha Allen; Christine Racette; Steven B Maron; Chih-Yi Liao; Blase N Polite; Hedy L Kindler; Kiran Turaga; Vivek N Prachand; Kevin K Roggin; Mark K Ferguson; Mitchell C Posner
Journal:  JAMA Netw Open       Date:  2020-02-05

4.  Adjuvant chemotherapy is superior to chemoradiation after D2 surgery for gastric cancer in the per-protocol analysis of the randomized CRITICS trial.

Authors:  W O de Steur; R M van Amelsfoort; H H Hartgrink; H Putter; E Meershoek-Klein Kranenbarg; N C T van Grieken; J W van Sandick; Y H M Claassen; J P B M Braak; E P M Jansen; K Sikorska; H van Tinteren; I Walraven; P Lind; M Nordsmark; M I van Berge Henegouwen; H W M van Laarhoven; A Cats; M Verheij; C J H van de Velde
Journal:  Ann Oncol       Date:  2020-11-20       Impact factor: 32.976

5.  Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas.

Authors:  John T Mullen; Theodore S Hong; Jennifer Y Wo; Jeffrey W Clark; Christine E Eyler; Mari Mino-Kenudson; Samuel J Klempner; Jill N Allen; Florence K Keane; Aparna R Parikh; Eric Roeland; Lorraine C Drapek; David P Ryan; Ryan B Corcoran; Emily Van Seventer; Isobel J Fetter; Heather A Shahzade; Melin J Khandekar; Michael Lanuti; Christopher R Morse; Rebecca S Heist; Christine A Ulysse; Benjamin Christopher; Christian Baglini; Beow Y Yeap
Journal:  Clin Cancer Res       Date:  2021-07-30       Impact factor: 12.531

  5 in total

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