Literature DB >> 3458812

Synthesis of transthyretin (pre-albumin) mRNA in choroid plexus epithelial cells, localized by in situ hybridization in rat brain.

A J Stauder, P W Dickson, A R Aldred, G Schreiber, F A Mendelsohn, P Hudson.   

Abstract

The sites of synthesis of transthyretin in the brain were investigated using in situ hybridization with [35S]-labeled recombinant cDNA probes specific for transthyretin mRNA. Autoradiography of hybridized coronal sections of rat brain revealed specific cellular localization of transthyretin mRNA in choroid plexus epithelial cells of the lateral, third, and fourth ventricles. Transferrin mRNA was also investigated and, in contrast to transthyretin mRNA, was localized mainly in the lateral ventricles. Our results indicate that substantial synthesis of transthyretin and transferrin mRNA may occur in the choroid plexus.

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Year:  1986        PMID： 3458812     DOI： 10.1177/34.7.3458812

Source DB:  PubMed          Journal:  J Histochem Cytochem        ISSN： 0022-1554            Impact factor:   2.479


  14 in total

1.  FRET studies of various conformational states adopted by transthyretin.

Authors:  Seyyed Abolghasem Ghadami; Francesco Bemporad; Benedetta Maria Sala; Guido Tiana; Stefano Ricagno; Fabrizio Chiti
Journal:  Cell Mol Life Sci       Date:  2017-05-06       Impact factor: 9.261

2.  Immunohistochemical study of ependymal neoplasms: histological subtypes and glial and epithelial characteristics.

Authors:  Y Kaneko; I Takeshita; T Matsushima; T Iwaki; T Tashima; M Fukui
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1990

3.  Cerebrospinal fluid soluble L-selectin (sCD62L) in meningoencephalitis.

Authors:  C Bührer; R Herold; D Stibenz; G Henze; M Obladen
Journal:  Arch Dis Child       Date:  1996-04       Impact factor: 3.791

4.  Delayed development of specific thyroid hormone-regulated events in transthyretin null mice.

Authors:  Julie A Monk; Natalie A Sims; Katarzyna M Dziegielewska; Roy E Weiss; Robert G Ramsay; Samantha J Richardson
Journal:  Am J Physiol Endocrinol Metab       Date:  2012-10-23       Impact factor: 4.310

5.  Distinct positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic mice.

Authors:  C Yan; R H Costa; J E Darnell; J D Chen; T A Van Dyke
Journal:  EMBO J       Date:  1990-03       Impact factor: 11.598

6.  Choroid plexus epithelial monolayers--a cell culture model from porcine brain.

Authors:  Carsten Baehr; Valeska Reichel; Gert Fricker
Journal:  Cerebrospinal Fluid Res       Date:  2006-12-21

Review 7.  Transport of thyroid hormones via the choroid plexus into the brain: the roles of transthyretin and thyroid hormone transmembrane transporters.

Authors:  Samantha J Richardson; Roshen C Wijayagunaratne; Damian G D'Souza; Veerle M Darras; Stijn L J Van Herck
Journal:  Front Neurosci       Date:  2015-03-03       Impact factor: 4.677

8.  A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M Mutation.

Authors:  Catarina S H Jesus; Zaida L Almeida; Daniela C Vaz; Tiago Q Faria; Rui M M Brito
Journal:  Int J Mol Sci       Date:  2016-08-31       Impact factor: 5.923

9.  Chronic lithium administration down regulates transthyretin mRNA expression in rat choroid plexus.

Authors:  David J Pulford; Fiona Adams; Brian Henry; David J Mallinson; Ian C Reid; Caroline A Stewart
Journal:  Neuropsychiatr Dis Treat       Date:  2006-12       Impact factor: 2.570

10.  A BMP-FGF morphogen toggle switch drives the ultrasensitive expression of multiple genes in the developing forebrain.

Authors:  Shyam Srinivasan; Jia Sheng Hu; D Spencer Currle; Ernest S Fung; Wayne B Hayes; Arthur D Lander; Edwin S Monuki
Journal:  PLoS Comput Biol       Date:  2014-02-13       Impact factor: 4.475
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