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Literature DB >> 34584058

Gene Therapy Approaches to Slow or Reverse Blindness From Inherited Retinal Degeneration: Growth Factors and Optogenetics.

Russell N Van Gelder.

Abstract

Entities: Chemical

Mesh：

Year: 2021 PMID： 34584058 PMCID： PMC8486303 DOI： 10.1097/IIO.0000000000000386

Source DB: PubMed Journal: Int Ophthalmol Clin ISSN： 0020-8167

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92 in total

Review 1. Gene editing prospects for treating inherited retinal diseases.

Authors: Daniela Benati; Clarissa Patrizi; Alessandra Recchia
Journal: J Med Genet Date: 2019-12-19 Impact factor: 6.318

2. Long-term protection of retinal structure but not function using RAAV.CNTF in animal models of retinitis pigmentosa.

Authors: F Q Liang; T S Aleman; N S Dejneka; L Dudus; K J Fisher; A M Maguire; S G Jacobson; J Bennett
Journal: Mol Ther Date: 2001-11 Impact factor: 11.454

3. Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration.

Authors: Pamela S Lagali; David Balya; Gautam B Awatramani; Thomas A Münch; Douglas S Kim; Volker Busskamp; Constance L Cepko; Botond Roska
Journal: Nat Neurosci Date: 2008-04-27 Impact factor: 24.884

4. Synergistic neuroprotective effect via simian lentiviral vector-mediated simultaneous gene transfer of human pigment epithelium-derived factor and human fibroblast growth factor-2 in rodent models of retinitis pigmentosa.

Authors: Masanori Miyazaki; Yasuhiro Ikeda; Yoshikazu Yonemitsu; Yoshinobu Goto; Ri-ichiro Kohno; Yusuke Murakami; Makoto Inoue; Yasuji Ueda; Mamoru Hasegawa; Shozo Tobimatsu; Katsuo Sueishi; Tatsuro Ishibashi
Journal: J Gene Med Date: 2008-12 Impact factor: 4.565

5. ASCL1 reprograms mouse Muller glia into neurogenic retinal progenitors.

Authors: Julia Pollak; Matthew S Wilken; Yumi Ueki; Kristen E Cox; Jane M Sullivan; Russell J Taylor; Edward M Levine; Thomas A Reh
Journal: Development Date: 2013-05-01 Impact factor: 6.868

6. In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration.

Authors: Prateek K Buch; Robert E MacLaren; Yanaí Durán; Kamaljit S Balaggan; Angus MacNeil; Frank C Schlichtenbrede; Alexander J Smith; Robin R Ali
Journal: Mol Ther Date: 2006-07-26 Impact factor: 11.454

Gene Therapy Approaches to Slow or Reverse Blindness From Inherited Retinal Degeneration: Growth Factors and Optogenetics.

Review 1. Gene editing prospects for treating inherited retinal diseases.

2. Long-term protection of retinal structure but not function using RAAV.CNTF in animal models of retinitis pigmentosa.

3. Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration.

4. Synergistic neuroprotective effect via simian lentiviral vector-mediated simultaneous gene transfer of human pigment epithelium-derived factor and human fibroblast growth factor-2 in rodent models of retinitis pigmentosa.

5. ASCL1 reprograms mouse Muller glia into neurogenic retinal progenitors.

6. In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration.

7. ChR2 mutants at L132 and T159 with improved operational light sensitivity for vision restoration.

8. Evaluation of the adeno-associated virus mediated long-term expression of channelrhodopsin-2 in the mouse retina.

9. Endothelin-2-mediated protection of mutant photoreceptors in inherited photoreceptor degeneration.

10. Restoration of the majority of the visual spectrum by using modified Volvox channelrhodopsin-1.

Review 1. Regenerative and restorative medicine for eye disease.