Husam M Salah1, Abdul Mannan Khan Minhas2, Muhammad Shahzeb Khan3, Safi U Khan4, Andrew P Ambrosy5, Vanessa Blumer6, Muthiah Vaduganathan7, Stephen J Greene8, Ambarish Pandey9, Marat Fudim10. 1. Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR. 2. Department of Medicine, Forrest General Hospital, Hattiesburg, MS. 3. Department of Medicine, University of Mississippi, Jackson, MS; Department of Medicine, Division of Cardiology, Duke University, Durham, NC. 4. Department of Medicine, West Virginia University, Morgantown, WV. 5. Department of Cardiology, Kaiser Permanente San Francisco Medical Center, San Francisco, CA; Division of Research, Kaiser Permanente Northern California, Oakland, CA. 6. Department of Medicine, Division of Cardiology, Duke University, Durham, NC. 7. Heart & Vascular Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. 8. Department of Medicine, Division of Cardiology, Duke University, Durham, NC; Duke Clinical Research Institute, Durham, NC. 9. Department of Medicine, Division of Cardiology, University Texas Southwestern and Parkland Health and Hospital System, Dallas, TX. 10. Department of Medicine, Division of Cardiology, Duke University, Durham, NC; Duke Clinical Research Institute, Durham, NC. Electronic address: marat.fudim@duke.edu.
Abstract
AIM: To determine the trends in hospitalizations for heart failure (HF), acute myocardial infarction (AMI), and stroke in the United States (US). METHOD AND RESULTS: A retrospective analysis of the National Inpatient Sample weighted data between January 1, 2004 and December 31, 2018 which included hospitalized adults ≥18 years with a primary discharge diagnosis of HF, AMI, or stroke using International Classification of Diseases-9/10 administrative codes. Main outcomes were hospitalization for HF, AMI, and stroke per 1000 United States adults, length of stay, and in-hospital mortality. There were 33.4 million hospitalizations for HF, AMI, and stroke, with most being for HF (48%). After the initial decline in HF hospitalizations (5.3 hospitalizations/1000 US adults in 2004 to 4 hospitalizations/1000 US adults in 2013, P < .001), there was a progressive increase in HF hospitalizations between 2013 and 2018 (4.0 hospitalizations/1000 US adults in 2013 to 4.9 hospitalizations/1000 US adults in 2018; P < .001). Hospitalization for AMI decreased (3.1 hospitalizations/1000 US adults in 2004 to 2.5 hospitalizations/1000 US adults in 2010, P < .001) and remained stable between 2010 and 2018. There was no significant change for hospitalization for stroke between 2004 and 2011 (2.3 hospitalizations/1000 US adults in 2004 vs 2.3 hospitalizations per 1000 US adults in 2011, P = .614); however, there was a small but significant increase in hospitalization for stroke after 2011 that reached 2.5 hospitalizations/1000 US adults in 2018. Adjusted length of stay and in-hospital mortality decreased for HF, AMI, and stroke hospitalizations. CONCLUSIONS: In contrast to the trend of AMI and stroke hospitalizations, a progressive increase in hospitalizations for HF has occurred since 2013. From 2004 to 2018, in-hospital mortality has decreased for HF, AMI, and stroke hospitalizations.
AIM: To determine the trends in hospitalizations for heart failure (HF), acute myocardial infarction (AMI), and stroke in the United States (US). METHOD AND RESULTS: A retrospective analysis of the National Inpatient Sample weighted data between January 1, 2004 and December 31, 2018 which included hospitalized adults ≥18 years with a primary discharge diagnosis of HF, AMI, or stroke using International Classification of Diseases-9/10 administrative codes. Main outcomes were hospitalization for HF, AMI, and stroke per 1000 United States adults, length of stay, and in-hospital mortality. There were 33.4 million hospitalizations for HF, AMI, and stroke, with most being for HF (48%). After the initial decline in HF hospitalizations (5.3 hospitalizations/1000 US adults in 2004 to 4 hospitalizations/1000 US adults in 2013, P < .001), there was a progressive increase in HF hospitalizations between 2013 and 2018 (4.0 hospitalizations/1000 US adults in 2013 to 4.9 hospitalizations/1000 US adults in 2018; P < .001). Hospitalization for AMI decreased (3.1 hospitalizations/1000 US adults in 2004 to 2.5 hospitalizations/1000 US adults in 2010, P < .001) and remained stable between 2010 and 2018. There was no significant change for hospitalization for stroke between 2004 and 2011 (2.3 hospitalizations/1000 US adults in 2004 vs 2.3 hospitalizations per 1000 US adults in 2011, P = .614); however, there was a small but significant increase in hospitalization for stroke after 2011 that reached 2.5 hospitalizations/1000 US adults in 2018. Adjusted length of stay and in-hospital mortality decreased for HF, AMI, and stroke hospitalizations. CONCLUSIONS: In contrast to the trend of AMI and stroke hospitalizations, a progressive increase in hospitalizations for HF has occurred since 2013. From 2004 to 2018, in-hospital mortality has decreased for HF, AMI, and stroke hospitalizations.
Authors: Husam M Salah; Subhi J Al'Aref; Muhammad Shahzeb Khan; Malek Al-Hawwas; Srikanth Vallurupalli; Jawahar L Mehta; J Paul Mounsey; Stephen J Greene; Darren K McGuire; Renato D Lopes; Marat Fudim Journal: Cardiovasc Diabetol Date: 2022-02-05 Impact factor: 9.951
Authors: Husam M Salah; Abdul Mannan Khan Minhas; Muhammad Shahzeb Khan; Safi U Khan; Andrew P Ambrosy; Vanessa Blumer; Muthiah Vaduganathan; Stephen J Greene; Ambarish Pandey; Marat Fudim Journal: ESC Heart Fail Date: 2022-01-30
Authors: Douglas Darden; Pamela N Peterson; Xin Xin; Muhammad Bilal Munir; Karl E Minges; Ilan Goldenberg; Jeanne E Poole; Gregory K Feld; Ulrika Birgersdotter-Green; Jeptha P Curtis; Jonathan C Hsu Journal: Heart Rhythm O2 Date: 2022-04-02