Literature DB >> 3458228

In vivo-like growth of human tumors in vitro.

A E Freeman, R M Hoffman.   

Abstract

We show that diverse human tumors obtained directly from surgery or biopsy can grow at high frequency in vitro for long periods of time and still maintain many of their in vivo properties. The in vivo properties maintained in vitro include three-dimensional growth; maintenance of tissue organization and structure, including changes associated with oncogenic transformation; retention of differentiated function; tumorigenicity; and the growth of multiple types of cells from a single tumor.

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Year:  1986        PMID： 3458228      PMCID： PMC323366          DOI： 10.1073/pnas.83.8.2694

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  47 in total

1.  Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes.

Authors:  D F Clayton; J E Darnell
Journal:  Mol Cell Biol       Date:  1983-09       Impact factor: 4.272

2.  Comparison of collagen gels and mammary extracellular matrix as substrata for study of terminal differentiation in rabbit mammary epithelial cells.

Authors:  C J Wilde; H R Hasan; R J Mayer
Journal:  Exp Cell Res       Date:  1984-04       Impact factor: 3.905

3.  Significance of three-dimensional growth patterns of mammary tissues in collagen gels.

Authors:  E M Lawler; F R Miller; G H Heppner
Journal:  In Vitro       Date:  1983-08

4.  Assessing tumor drug sensitivity by a new in vitro assay which preserves tumor heterogeneity and subpopulation interactions.

Authors:  B E Miller; F R Miller; G H Heppner
Journal:  J Cell Physiol Suppl       Date:  1984

5.  Interaction of mouse mammary epithelial cells with collagen substrata: regulation of casein gene expression and secretion.

Authors:  E Y Lee; W H Lee; C S Kaetzel; G Parry; M J Bissell
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

6.  Invasiveness and ploidy of human mammary carcinomas in short-term culture.

Authors:  H S Smith; L A Liotta; M C Hancock; S R Wolman; A J Hackett
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

7.  Exceptional lethality for nude mice of cells derived from a primary human melanoma.

Authors:  A Lockshin; B C Giovanella; P D De Ipolyi; L J Williams; J T Mendoza; S O Yim; J S Stehlin
Journal:  Cancer Res       Date:  1985-01       Impact factor: 12.701

8.  Cell proliferation and milk protein gene expression in rabbit mammary cell cultures.

Authors:  Y M Suard; M T Haeuptle; E Farinon; J P Kraehenbuhl
Journal:  J Cell Biol       Date:  1983-05       Impact factor: 10.539

9.  Modulation of secreted proteins of mouse mammary epithelial cells by the collagenous substrata.

Authors:  E Y Lee; G Parry; M J Bissell
Journal:  J Cell Biol       Date:  1984-01       Impact factor: 10.539

10.  Effect of cell shape change on the function and differentiation of rabbit mammary cells in culture.

Authors:  M T Haeuptle; Y L Suard; E Bogenmann; H Reggio; L Racine; J P Kraehenbuhl
Journal:  J Cell Biol       Date:  1983-05       Impact factor: 10.539
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  54 in total

1.  Long-term passage of human tissues in vitro as three-dimensional histolines.

Authors:  H K Slocum; K Tòth; L Li; S G Chang; R M Hoffman; Y M Rustum
Journal:  In Vitro Cell Dev Biol       Date:  1992 Sep-Oct

2.  Glucose consumption end point in primary histoculture indicates recovery of human tumors from drug treatment.

Authors:  S G Chang; H K Slocum; K Tòth; R M Hoffman; S D Perrapato; R P Huben; Y Rustum
Journal:  In Vitro Cell Dev Biol       Date:  1992 Sep-Oct

3.  Hair growth in vitro from histocultured skin.

Authors:  L Li; R Paus; L B Margolis; R M Hoffman
Journal:  In Vitro Cell Dev Biol       Date:  1992 Jul-Aug

4.  Governing step of metastasis visualized in vitro.

Authors:  T Chishima; M Yang; Y Miyagi; L Li; Y Tan; E Baranov; H Shimada; A R Moossa; S Penman; R M Hoffman
Journal:  Proc Natl Acad Sci U S A       Date:  1997-10-14       Impact factor: 11.205

5.  Influence of HLDF Differentiation Factor on Nonspecific Invasive Breast Carcinoma in vitro.

Authors:  A I Autenshlyus; I P Zhurakovsky; K I Davletova; A P Bogachuk; V V Lyakhovich; V M Lipkin
Journal:  Dokl Biochem Biophys       Date:  2020-12-25       Impact factor: 0.788

6.  Targeting antibodies to live tumor tissue in 3-D histoculture.

Authors:  F Guadagni; L Li; R M Hoffman
Journal:  In Vitro Cell Dev Biol       Date:  1992-05

7.  In vivo growth patterns of human lung tumors in three-dimensional histoculture.

Authors:  B Baibakov; G A Frank; N Sergeeva; I Novikova; T Youngkin; K M Connors; R M Hoffman; L B Margolis
Journal:  In Vitro Cell Dev Biol       Date:  1991-12

8.  Skin toxicity determined in vitro by three-dimensional, native-state histoculture.

Authors:  L N Li; L B Margolis; R M Hoffman
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-01       Impact factor: 11.205

9.  Extracellular vesicles generated by placental tissues ex vivo: A transport system for immune mediators and growth factors.

Authors:  Wendy Fitzgerald; Nardhy Gomez-Lopez; Offer Erez; Roberto Romero; Leonid Margolis
Journal:  Am J Reprod Immunol       Date:  2018-05-04       Impact factor: 3.886

10.  Chemosensitivity assessed by collagen gel droplet embedded culture drug sensitivity test, and MDR1, MRP1, and MRP2 mRNA expression in human colorectal adenocarcinomas.

Authors:  Takako Nakahara; Toshiyuki Sakaeda; Tsutomu Nakamura; Takao Tamura; Chiharu Nishioka; Nobuo Aoyama; Noboru Okamura; Toshiro Shirakawa; Akinobu Gotoh; Takashi Kamigaki; Masakazu Ohno; Yoshikazu Kuroda; Masafumi Matsuo; Masato Kasuga; Katsuhiko Okumura
Journal:  Pharm Res       Date:  2004-03       Impact factor: 4.200
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