Literature DB >> 34579972

Evolutionary impact of chimeric RNAs on generating phenotypic plasticity in human cells.

Sumit Mukherjee1, Milana Frenkel-Morgenstern2.   

Abstract

Chimeric RNAs are generated by the fusion of the exons or introns of two genes. The generation of chimeric RNAs is important for the functional expansion of cells. Here, we describe the functional implications of chimeric RNAs for generating phenotypic plasticity from an evolutionary perspective.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  cancer evolution; chimeric RNA; gene fusion; phenotypic plasticity

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Substances:

Year:  2021        PMID: 34579972     DOI: 10.1016/j.tig.2021.08.015

Source DB:  PubMed          Journal:  Trends Genet        ISSN: 0168-9525            Impact factor:   11.639


  2 in total

Review 1.  Chimeric RNAs Discovered by RNA Sequencing and Their Roles in Cancer and Rare Genetic Diseases.

Authors:  Yunan Sun; Hui Li
Journal:  Genes (Basel)       Date:  2022-04-22       Impact factor: 4.141

2.  The Landscape of Novel Expressed Chimeric RNAs in Rheumatoid Arthritis.

Authors:  Rajesh Detroja; Sumit Mukherjee; Milana Frenkel-Morgenstern
Journal:  Cells       Date:  2022-03-24       Impact factor: 6.600

  2 in total

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