Literature DB >> 3457468

Amplification and rearrangement of Hu-ets-1 in leukemia and lymphoma with involvement of 11q23.

U Rovigatti, D K Watson, J J Yunis.   

Abstract

The Hu-ets-1 oncogene was found to be rearranged and amplified 30-fold in one case of acute myelomonocytic leukemia in which a homogeneously staining region occurred on 11q23; the oncogene was rearranged and amplified approximately tenfold in a case of small lymphocytic cell lymphoma with an inverted insertion that also involved band 11q23. This work suggests that Hu-ets-1 is an unusual oncogene that can help explain the common involvement of chromosome band 11q23 in various subtypes of hematopoietic malignancies.

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Year:  1986        PMID： 3457468     DOI： 10.1126/science.3457468

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  16 in total

1.  Karyotype peculiarities of human colorectal adenocarcinomas.

Authors:  L N Konstantinova; E W Fleischman; V I Knisch; A G Perevozchikov; B P Kopnin
Journal:  Hum Genet       Date:  1991-03       Impact factor: 4.132

Review 2.  Molecular mechanisms of ETS transcription factor-mediated tumorigenesis.

Authors:  Adwitiya Kar; Arthur Gutierrez-Hartmann
Journal:  Crit Rev Biochem Mol Biol       Date:  2013-09-25       Impact factor: 8.250

3.  Definition of an acquired 11q deletion in a tumorigenic human monocytic cell line.

Authors:  E Maserati; L Romitti; M L Carrozza; A Lombardo; R Revoltella
Journal:  Hum Genet       Date:  1990-03       Impact factor: 4.132

4.  Chromosome analysis of 30 cases of non-Hodgkin's lymphoma.

Authors:  G Chenevix-Trench; J A Brown; G B Tyler; F G Behm
Journal:  Med Oncol Tumor Pharmacother       Date:  1988

Review 5.  Human cancer and cellular oncogenes.

Authors:  S Nishimura; T Sekiya
Journal:  Biochem J       Date:  1987-04-15       Impact factor: 3.857

6.  Detection of chromosome 11q23 involving translocations by pulsed field gel electrophoresis.

Authors:  J Finke; R Kunzmann; W Lange
Journal:  Ann Hematol       Date:  1994-03       Impact factor: 3.673

7.  Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia.

Authors:  Jian Zhong Tang; Catherine L Carmichael; Wei Shi; Donald Metcalf; Ashley P Ng; Craig D Hyland; Nancy A Jenkins; Neal G Copeland; Viive M Howell; Zhizhuang Joe Zhao; Gordon K Smyth; Benjamin T Kile; Warren S Alexander
Journal:  Proc Natl Acad Sci U S A       Date:  2013-03-26       Impact factor: 11.205

8.  The human c-ros gene (ROS) is located at chromosome region 6q16----6q22.

Authors:  L Nagarajan; E Louie; Y Tsujimoto; P C Balduzzi; K Huebner; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

Review 9.  Ets transcription factors in intestinal morphogenesis, homeostasis and disease.

Authors:  Paul Jedlicka; Arthur Gutierrez-Hartmann
Journal:  Histol Histopathol       Date:  2008-11       Impact factor: 2.303

Review 10.  Review of Ets1 structure, function, and roles in immunity.

Authors:  Lee Ann Garrett-Sinha
Journal:  Cell Mol Life Sci       Date:  2013-01-05       Impact factor: 9.261
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