Literature DB >> 3456904

The human osteosarcoma cell line U-2 OS expresses a 3.8 kilobase mRNA which codes for the sequence of the PDGF-B chain.

H A Weich, W Sebald, H U Schairer, J Hoppe.   

Abstract

A cDNA clone of about 2500 base pairs was prepared from the human osteosarcoma cell line U-2 OS by hybridizing with a v-sis probe. Sequence analysis showed that this cDNA contains the coding region for the PDGF-B chain. It is discussed that the mitogen secreted by these osteosarcoma cells contains the PDGF-B chain and is probably a homodimer of two B-chains.

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Year:  1986        PMID: 3456904     DOI: 10.1016/0014-5793(86)80433-1

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  1 in total

1.  AIDS-associated Kaposi's sarcoma-derived cells in long-term culture express and synthesize smooth muscle alpha-actin.

Authors:  H A Weich; S Z Salahuddin; P Gill; S Nakamura; R C Gallo; J Folkmann
Journal:  Am J Pathol       Date:  1991-12       Impact factor: 4.307

  1 in total

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