| Literature DB >> 3456829 |
J Katsuyama, P R Papenhausen, F Herz, P Gazivoda, A Hirano, L G Koss.
Abstract
Cytogenetic analyses of eight meningiomas grown in culture for 1 week are reported. Normal karyotypes were found in three cases and hypodiploidy in the remaining five. In the five hypodiploid meningiomas, one chromosome #22 was missing in four cases, and one case exhibited a 22q- deletion. In four of these five cases, chromosome #14 was either lost or altered. Chromosome #1 was lost or altered in three, and chromosome #6 in two. These findings lend further support for the association of total or partial loss of chromosome #22 in meningiomas and suggest the involvement of other chromosomes in the clonal evolution of these tumors.Entities:
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Year: 1986 PMID: 3456829 DOI: 10.1016/0165-4608(86)90138-x
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN: 0165-4608