Literature DB >> 34565899

Charting a Course toward a New Vaccine Strategy.

Gerard M Nadal1.   

Abstract

There has been a long-simmering disquiet in Catholic circles regarding the use cell lines derived from aborted fetal tissue. This concern has exploded into the public consciousness given the use of questionable cell lines in the development and/or testing of the current COVID-19 vaccines, and the debate within the Church over the permissibility of using these vaccines. The history of cell culture and how the biological community came to rely on HEK293 fetal cell lines is explored, as is the way forward, moving the biotech industry away from ethically problematic cells and toward the development of more ethically sourced cell lines. The role of the Church in leading the way forward and the acceptable use of medicines utilizing HEK293 cell lines are all explored. © Catholic Medical Association 2021.

Entities:  

Keywords:  COVID-19; Ethics; HEK293; Morality; Pandemic; Sars-CoV-2; Vaccines

Year:  2021        PMID: 34565899      PMCID: PMC8375380          DOI: 10.1177/00243639211014621

Source DB:  PubMed          Journal:  Linacre Q        ISSN: 0024-3639


  11 in total

1.  Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid.

Authors:  J D WATSON; F H CRICK
Journal:  Nature       Date:  1953-04-25       Impact factor: 49.962

2.  A statement by the editors of The Lancet.

Authors:  Richard Horton
Journal:  Lancet       Date:  2004-03-06       Impact factor: 79.321

Review 3.  Advancements in reprogramming strategies for the generation of induced pluripotent stem cells.

Authors:  Mei I Lai; Wai Yeng Wendy-Yeo; Rajesh Ramasamy; Norshariza Nordin; Rozita Rosli; Abhi Veerakumarasivam; Syahril Abdullah
Journal:  J Assist Reprod Genet       Date:  2011-03-09       Impact factor: 3.412

4.  Characteristics of a human cell line transformed by DNA from human adenovirus type 5.

Authors:  F L Graham; J Smiley; W C Russell; R Nairn
Journal:  J Gen Virol       Date:  1977-07       Impact factor: 3.891

Review 5.  mRNA vaccines - a new era in vaccinology.

Authors:  Norbert Pardi; Michael J Hogan; Frederick W Porter; Drew Weissman
Journal:  Nat Rev Drug Discov       Date:  2018-01-12       Impact factor: 84.694

6.  Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children.

Authors:  A J Wakefield; S H Murch; A Anthony; J Linnell; D M Casson; M Malik; M Berelowitz; A P Dhillon; M A Thomson; P Harvey; A Valentine; S E Davies; J A Walker-Smith
Journal:  Lancet       Date:  1998-02-28       Impact factor: 79.321

7.  Bioethics, Conscience, and Prudence in the Time of COVID.

Authors:  Barbara Golder
Journal:  Linacre Q       Date:  2021-02-05

Review 8.  Post-acute COVID-19 syndrome.

Authors:  Ani Nalbandian; Kartik Sehgal; Aakriti Gupta; Mahesh V Madhavan; Claire McGroder; Jacob S Stevens; Joshua R Cook; Anna S Nordvig; Daniel Shalev; Tejasav S Sehrawat; Neha Ahluwalia; Behnood Bikdeli; Donald Dietz; Caroline Der-Nigoghossian; Nadia Liyanage-Don; Gregg F Rosner; Elana J Bernstein; Sumit Mohan; Akinpelumi A Beckley; David S Seres; Toni K Choueiri; Nir Uriel; John C Ausiello; Domenico Accili; Daniel E Freedberg; Matthew Baldwin; Allan Schwartz; Daniel Brodie; Christine Kim Garcia; Mitchell S V Elkind; Jean M Connors; John P Bilezikian; Donald W Landry; Elaine Y Wan
Journal:  Nat Med       Date:  2021-03-22       Impact factor: 53.440

9.  Independent functions of viral protein and nucleic acid in growth of bacteriophage.

Authors:  A D HERSHEY; M CHASE
Journal:  J Gen Physiol       Date:  1952-05       Impact factor: 4.086

Review 10.  SARS, MERS and COVID-19: clinical manifestations and organ-system complications: a mini review.

Authors:  Jad Gerges Harb; Hussein A Noureldine; Georges Chedid; Mariam Nour Eldine; Dany Abou Abdallah; Nancy Falco Chedid; Wared Nour-Eldine
Journal:  Pathog Dis       Date:  2020-06-01       Impact factor: 3.166

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