Literature DB >> 34565558

Histone Deacetylases in the Control of Epidermal Homeostasis: From Chromatin Biology toward Therapy.

Vladimir A Botchkarev1, Andrey A Sharov2.   

Abstract

Histone deacetylases (HDACs) induce gene repression and modify the activity of nonhistone proteins. In a new article in the Journal of Investigative Dermatology, Zhu et al. (2021) demonstrate essential roles for HDAC1/2 in maintaining keratinocyte proliferation and survival in adult epidermis and basal cell carcinoma, thus providing a rationale for using HDAC inhibitors for the treatment of hyperproliferative and neoplastic skin disorders.
Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2021        PMID： 34565558      PMCID： PMC8734647          DOI： 10.1016/j.jid.2021.06.021

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  11 in total

1.  Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.

Authors:  Marina Grachtchouk; Joanna Pero; Steven H Yang; Alexandre N Ermilov; L Evan Michael; Aiqin Wang; Dawn Wilbert; Rajiv M Patel; Jennifer Ferris; James Diener; Mary Allen; Seokchun Lim; Li-Jyun Syu; Monique Verhaegen; Andrzej A Dlugosz
Journal:  J Clin Invest       Date:  2011-04-25       Impact factor: 14.808

2.  Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells.

Authors:  Matthew LeBoeuf; Anne Terrell; Sohum Trivedi; Satrajit Sinha; Jonathan A Epstein; Eric N Olson; Edward E Morrisey; Sarah E Millar
Journal:  Dev Cell       Date:  2010-11-18       Impact factor: 12.270

Review 3.  Epigenetic control in skin development, homeostasis and injury repair.

Authors:  Sangjo Kang; Gopal Chovatiya; Tudorita Tumbar
Journal:  Exp Dermatol       Date:  2019-02-12       Impact factor: 3.960

Review 4.  Epigenetic modulation and understanding of HDAC inhibitors in cancer therapy.

Authors:  M Janaki Ramaiah; Anjana Devi Tangutur; Rajasekhar Reddy Manyam
Journal:  Life Sci       Date:  2021-04-16       Impact factor: 5.037

Review 5.  p53/p63/p73 in the epidermis in health and disease.

Authors:  Vladimir A Botchkarev; Elsa R Flores
Journal:  Cold Spring Harb Perspect Med       Date:  2014-08-01       Impact factor: 6.915

Review 6.  The Yin and Yang of Chromatin Dynamics In Stem Cell Fate Selection.

Authors:  Rene C Adam; Elaine Fuchs
Journal:  Trends Genet       Date:  2015-12-13       Impact factor: 11.639

Review 7.  Emerging roles of lysine methylation on non-histone proteins.

Authors:  Xi Zhang; Yaling Huang; Xiaobing Shi
Journal:  Cell Mol Life Sci       Date:  2015-07-31       Impact factor: 9.261

Review 8.  The physiological roles of histone deacetylase (HDAC) 1 and 2: complex co-stars with multiple leading parts.

Authors:  Richard D W Kelly; Shaun M Cowley
Journal:  Biochem Soc Trans       Date:  2013-06       Impact factor: 5.407

9.  Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors.

Authors:  Jay H Kalin; Muzhou Wu; Andrea V Gomez; Yun Song; Jayanta Das; Dawn Hayward; Nkosi Adejola; Mingxuan Wu; Izabela Panova; Hye Jin Chung; Edward Kim; Holly J Roberts; Justin M Roberts; Polina Prusevich; Jeliazko R Jeliazkov; Shourya S Roy Burman; Louise Fairall; Charles Milano; Abdulkerim Eroglu; Charlotte M Proby; Albena T Dinkova-Kostova; Wayne W Hancock; Jeffrey J Gray; James E Bradner; Sergio Valente; Antonello Mai; Nicole M Anders; Michelle A Rudek; Yong Hu; Byungwoo Ryu; John W R Schwabe; Andrea Mattevi; Rhoda M Alani; Philip A Cole
Journal:  Nat Commun       Date:  2018-01-04       Impact factor: 14.919

Review 10.  Master regulatory role of p63 in epidermal development and disease.

Authors:  Eduardo Soares; Huiqing Zhou
Journal:  Cell Mol Life Sci       Date:  2017-11-04       Impact factor: 9.261
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.