Literature DB >> 34559988

BETting on BRD4 inhibition to combat adaptive resistance to CAR T cell therapy in glioblastoma.

Caitlin R Hopkins1, Joseph A Fraietta2.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2021        PMID： 34559988      PMCID： PMC8531136          DOI： 10.1016/j.ymthe.2021.09.008

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   12.910


× No keyword cloud information.
  12 in total

1.  Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma.

Authors:  Stephanie L Goff; Richard A Morgan; James C Yang; Richard M Sherry; Paul F Robbins; Nicholas P Restifo; Steven A Feldman; Yong-Chen Lu; Lily Lu; Zhili Zheng; Liqiang Xi; Monica Epstein; Lori S McIntyre; Parisa Malekzadeh; Mark Raffeld; Howard A Fine; Steven A Rosenberg
Journal:  J Immunother       Date:  2019-05       Impact factor: 4.456

2.  Cancer Statistics, 2021.

Authors:  Rebecca L Siegel; Kimberly D Miller; Hannah E Fuchs; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2021-01-12       Impact factor: 508.702

3.  Declines in Cancer Death Rates Among Children and Adolescents in the United States, 1999-2014.

Authors:  Sally C Curtin; Arialdi M Minino; Robert N Anderson
Journal:  NCHS Data Brief       Date:  2016-09

Review 4.  Functions of bromodomain-containing proteins and their roles in homeostasis and cancer.

Authors:  Takao Fujisawa; Panagis Filippakopoulos
Journal:  Nat Rev Mol Cell Biol       Date:  2017-01-05       Impact factor: 94.444

5.  A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.

Authors:  Donald M O'Rourke; MacLean P Nasrallah; Arati Desai; Jan J Melenhorst; Keith Mansfield; Jennifer J D Morrissette; Maria Martinez-Lage; Steven Brem; Eileen Maloney; Angela Shen; Randi Isaacs; Suyash Mohan; Gabriela Plesa; Simon F Lacey; Jean-Marc Navenot; Zhaohui Zheng; Bruce L Levine; Hideho Okada; Carl H June; Jennifer L Brogdon; Marcela V Maus
Journal:  Sci Transl Med       Date:  2017-07-19       Impact factor: 17.956

Review 6.  Treatment of Glioblastoma.

Authors:  Joo Yeon Nam; John F de Groot
Journal:  J Oncol Pract       Date:  2017-10       Impact factor: 3.840

7.  HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial.

Authors:  Nabil Ahmed; Vita Brawley; Meenakshi Hegde; Kevin Bielamowicz; Mamta Kalra; Daniel Landi; Catherine Robertson; Tara L Gray; Oumar Diouf; Amanda Wakefield; Alexia Ghazi; Claudia Gerken; Zhongzhen Yi; Aidin Ashoori; Meng-Fen Wu; Hao Liu; Cliona Rooney; Gianpietro Dotti; Adrian Gee; Jack Su; Yvonne Kew; David Baskin; Yi Jonathan Zhang; Pamela New; Bambi Grilley; Milica Stojakovic; John Hicks; Suzanne Z Powell; Malcolm K Brenner; Helen E Heslop; Robert Grossman; Winfried S Wels; Stephen Gottschalk
Journal:  JAMA Oncol       Date:  2017-08-01       Impact factor: 31.777

8.  BRD4 inhibition boosts the therapeutic effects of epidermal growth factor receptor-targeted chimeric antigen receptor T cells in glioblastoma.

Authors:  Lin Xia; Jun-Yi Liu; Zao-Zao Zheng; Yu-Jie Chen; Jian-Cheng Ding; Ya-Hong Hu; Guo-Sheng Hu; Ning-Shao Xia; Wen Liu
Journal:  Mol Ther       Date:  2021-05-29       Impact factor: 12.910

Review 9.  The Management of Brain Metastases-Systematic Review of Neurosurgical Aspects.

Authors:  Martin A Proescholdt; Petra Schödel; Christian Doenitz; Tobias Pukrop; Julius Höhne; Nils Ole Schmidt; Karl-Michael Schebesch
Journal:  Cancers (Basel)       Date:  2021-03-31       Impact factor: 6.639
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.