Literature DB >> 3455895

Genetic analysis of the proximal portion of the mouse t complex: evidence for a second inversion within t haplotypes.

B Herrmann, M Bućan, P E Mains, A M Frischauf, L M Silver, H Lehrach.   

Abstract

Genomic sequences derived from the mouse t complex by a microdissection cloning technique have been used as tools to obtain high resolution genetic maps of the wild-type and t haplotype forms of the most proximal portion of chromosome 17. Genetic mapping was performed through a recombinant inbred strain analysis and an analysis of partial t haplotypes. The accumulated data demonstrate the existence of a large inversion of genetic material, encompassing the loci of T and qk, within the proximal portion of t haplotypes. This newly described proximal inversion and the previously described distal inversion provide an explanation for the suppression of recombination observed along the length of t haplotype DNA in heterozygous mice.

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Year:  1986        PMID： 3455895     DOI： 10.1016/0092-8674(86)90468-x

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  83 in total

1.  New molecular markers for the distal end of the t-complex and their relationships to mutations affecting mouse development.

Authors:  T Ebersole; F Lai; K Artzt
Journal:  Genetics       Date:  1992-05       Impact factor: 4.562

2.  Evolution of the mouse H-2K region: a hot spot of mutation associated with genes transcribed in embryos and/or germ cells.

Authors:  Y I Yeom; K Abe; K Artzt
Journal:  Genetics       Date:  1992-03       Impact factor: 4.562

3.  Pseudoautosomal repeat displays higher variability in blacks than in Caucasians.

Authors:  G A Rappold; A Henke; M Pohlschmid; T H Huisman
Journal:  Hum Genet       Date:  1992-03       Impact factor: 4.132

Review 4.  Long-range walking techniques in positional cloning strategies.

Authors:  L Stubbs
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

5.  Molecular organization of the D-Qa region of t-haplotypes suggests that recombination is an important mechanism for generating genetic diversity of the major histocompatibility complex.

Authors:  H Uehara; K Abe; L Flaherty; D Bennett; K Artzt
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

6.  Submegabase clusters of unstable tandem repeats unique to the Tla region of mouse t haplotypes.

Authors:  H Uehara; T Ebersole; D Bennett; K Artzt
Journal:  Genetics       Date:  1990-12       Impact factor: 4.562

7.  Genetic and molecular analysis of the proximal region of the mouse t-complex using new molecular probes and partial t-haplotypes.

Authors:  C A Howard; G R Gummere; M F Lyon; D Bennett; K Artzt
Journal:  Genetics       Date:  1990-12       Impact factor: 4.562

8.  Genetic analysis of a mouse t complex locus that is homologous to a kidney cDNA clone.

Authors:  E A Mann; L M Silver; R W Elliott
Journal:  Genetics       Date:  1986-11       Impact factor: 4.562

9.  The mouse plasminogen locus maps to the recombination breakpoints of the tLub2 and TtOrl partial t haplotypes but is not at the tw73 locus.

Authors:  N Schweifer; D P Barlow
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

10.  Intra-H-2 recombination in t haplotypes shows a hot spot and close linkage of 1tw5 to H-2K.

Authors:  K Artzt; K Abe; H Uehara; D Bennett
Journal:  Immunogenetics       Date:  1988       Impact factor: 2.846
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