Literature DB >> 3455870

Cytogenetic investigations in childhood chronic myelocytic leukemia.

F Ghione, C Mecucci, M Symann, J L Michaux, M Casteels-Van Daele, H Van den Berghe.   

Abstract

Cytogenetic studies were performed on 25 chronic myelogenous leukemia patients aged between 6 mo and 19 yr. Of these, 14 presented with the adult form and 11 with the juvenile form of the disease. In patients with the adult type, 12 of 14 had a Ph chromosome and additional anomalies appearing during blastic transformation. In patients with the juvenile form, 6 of 11 had a monosomy 7 and a short survival time (median 10 mo). Salient features of these patients, as well as a survey of the pertinent literature on the subject, are presented in this paper.

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Year:  1986        PMID: 3455870     DOI: 10.1016/0165-4608(86)90090-7

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  3 in total

1.  Cytogenetics investigation in childhood chronic myeloid leukemia.

Authors:  D Chinnappan; I C Verma; V P Choudhry; L S Arya
Journal:  Indian J Pediatr       Date:  2000-02       Impact factor: 1.967

Review 2.  Cytogenetics in childhood leukemias and malignant lymphomas.

Authors:  R Abe; Y Maruyama
Journal:  Indian J Pediatr       Date:  1993 Mar-Apr       Impact factor: 1.967

3.  Retroviral integration at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels.

Authors:  D A Largaespada; J D Shaughnessy; N A Jenkins; N G Copeland
Journal:  J Virol       Date:  1995-08       Impact factor: 5.103

  3 in total

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