Literature DB >> 34556297

Autocrine and paracrine effects of a novel podocyte gene, RARRES1.

Anqun Chen1, Kyung Lee2, John Cijiang He3.   

Abstract

Retinoic acid receptor responder protein 1 (RARRES1) has been identified as a novel gene for the regulation of podocyte function, and its expression is increased in glomerular disease and associated with disease progression. Increased expression of RARRES1 in podocytes leads to apoptosis through an autocrine effect. Möller-Hackbarth et al. recently found that RARRES1 expression is increased in the endothelial cells in some diseased kidneys to promote podocyte injury, likely through a paracrine effect.
Copyright © 2021 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

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Year:  2021        PMID： 34556297      PMCID： PMC9037532          DOI： 10.1016/j.kint.2021.07.008

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   18.998


  7 in total

1.  Retinoic acid improves nephrotoxic serum-induced glomerulonephritis through activation of podocyte retinoic acid receptor α.

Authors:  Yan Dai; Anqun Chen; Ruijie Liu; Leyi Gu; Shuchita Sharma; Weijing Cai; Fadi Salem; David J Salant; Jeffrey W Pippin; Stuart J Shankland; Marcus J Moeller; Norbert B Ghyselinck; Xiaoqiang Ding; Peter Y Chuang; Kyung Lee; John Cijiang He
Journal:  Kidney Int       Date:  2017-07-27       Impact factor: 10.612

2.  Disparate roles of retinoid acid signaling molecules in kidney disease.

Authors:  Anqun Chen; Yu Liu; Yu Lu; Kyung Lee; John Cijiang He
Journal:  Am J Physiol Renal Physiol       Date:  2021-03-01

3.  Soluble RARRES1 induces podocyte apoptosis to promote glomerular disease progression.

Authors:  Anqun Chen; Ye Feng; Han Lai; Wenjun Ju; Zhengzhe Li; Yu Li; Andrew Wang; Quan Hong; Fang Zhong; Chengguo Wei; Jia Fu; Tianjun Guan; Bichen Liu; Matthias Kretzler; Kyung Lee; John Cijiang He
Journal:  J Clin Invest       Date:  2020-10-01       Impact factor: 14.808

4.  Kruppel-like factor 15 (KLF15) is a key regulator of podocyte differentiation.

Authors:  Sandeep K Mallipattu; Ruijie Liu; Feng Zheng; Goutham Narla; Avi Ma'ayan; Steven Dikman; Mukesh K Jain; Moin Saleem; Vivette D'Agati; Paul Klotman; Peter Y Chuang; John C He
Journal:  J Biol Chem       Date:  2012-04-09       Impact factor: 5.157

5.  Tazarotene-induced gene 1 (TIG1), a novel retinoic acid receptor-responsive gene in skin.

Authors:  S Nagpal; S Patel; A T Asano; A T Johnson; M Duvic; R A Chandraratna
Journal:  J Invest Dermatol       Date:  1996-02       Impact factor: 8.551

Review 6.  Podocytopathies.

Authors:  Jeffrey B Kopp; Hans-Joachim Anders; Katalin Susztak; Manuel A Podestà; Giuseppe Remuzzi; Friedhelm Hildebrandt; Paola Romagnani
Journal:  Nat Rev Dis Primers       Date:  2020-08-13       Impact factor: 52.329

7.  Retinoic acid receptor responder1 promotes development of glomerular diseases via the Nuclear Factor-κB signaling pathway.

Authors:  Katja Möller-Hackbarth; Dina Dabaghie; Emmanuelle Charrin; Sonia Zambrano; Guillem Genové; Xidan Li; Annika Wernerson; Mark Lal; Jaakko Patrakka
Journal:  Kidney Int       Date:  2021-06-18       Impact factor: 10.612
  7 in total
  1 in total

1.  Inflammation-Driven Secretion Potential Is Upregulated in Osteoarthritic Fibroblast-Like Synoviocytes.

Authors:  Jakub Chwastek; Marta Kędziora; Małgorzata Borczyk; Michał Korostyński; Katarzyna Starowicz
Journal:  Int J Mol Sci       Date:  2022-10-05       Impact factor: 6.208
  1 in total

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