Literature DB >> 34550596

Practical Considerations and Challenges When Conducting an Individual Participant Data (IPD) Meta-Analysis.

Sarah J Nevitt1, Catrin Tudur Smith2.   

Abstract

This chapter provides a broad overview of the use of individual participant (sometimes referred to as patient) data (IPD ) within meta-analyses, the associated advantages of using IPD in meta-analysis compared to aggregate data, and when IPD should be used in meta-analysis.This chapter also outlines the steps of conducting an IPD meta-analysis, with practical guidance relating to requesting and obtaining IPD for meta-analysis. Challenges that can be associated with conducting an IPD meta-analysis are also discussed, including consideration of availability bias, when a subset of the relevant IPD is not available for meta-analysis.
© 2022. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Availability bias; Data sharing; Individual participant data; Individual patient data; Logistics; Meta-analysis

Mesh：

Year:  2022        PMID： 34550596     DOI： 10.1007/978-1-0716-1566-9_16

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  39 in total

1.  Meta-analysis of individual participant data: rationale, conduct, and reporting.

Authors:  Richard D Riley; Paul C Lambert; Ghada Abo-Zaid
Journal:  BMJ       Date:  2010-02-05

2.  When to include clinical study reports and regulatory documents in systematic reviews.

Authors:  Tom Jefferson; Peter Doshi; Isabelle Boutron; Su Golder; Carl Heneghan; Alex Hodkinson; Mark Jones; Carol Lefebvre; Lesley A Stewart
Journal:  BMJ Evid Based Med       Date:  2018-10-11

3.  Meta-analysis of individual patient data from randomized trials: a review of methods used in practice.

Authors:  Mark C Simmonds; Julian P T Higgins; Lesley A Stewart; Jayne F Tierney; Mike J Clarke; Simon G Thompson
Journal:  Clin Trials       Date:  2005       Impact factor: 2.486

4.  Practical methodology of meta-analyses (overviews) using updated individual patient data. Cochrane Working Group.

Authors:  L A Stewart; M J Clarke
Journal:  Stat Med       Date:  1995-10-15       Impact factor: 2.373

5.  To IPD or not to IPD? Advantages and disadvantages of systematic reviews using individual patient data.

Authors:  Lesley A Stewart; Jayne F Tierney
Journal:  Eval Health Prof       Date:  2002-03       Impact factor: 2.651

6.  Meta-analysis of the literature or of individual patient data: is there a difference?

Authors:  L A Stewart; M K Parmar
Journal:  Lancet       Date:  1993-02-13       Impact factor: 79.321

7.  The strengths and limitations of meta-analyses based on aggregate data.

Authors:  Gary H Lyman; Nicole M Kuderer
Journal:  BMC Med Res Methodol       Date:  2005-04-25       Impact factor: 4.615

8.  Individual participant data (IPD) meta-analyses of diagnostic and prognostic modeling studies: guidance on their use.

Authors:  Thomas P A Debray; Richard D Riley; Maroeska M Rovers; Johannes B Reitsma; Karel G M Moons
Journal:  PLoS Med       Date:  2015-10-13       Impact factor: 11.069

Review 9.  European Medicines Agency Policy 0070: an exploratory review of data utility in clinical study reports for academic research.

Authors:  Jean-Marc Ferran; Sarah J Nevitt
Journal:  BMC Med Res Methodol       Date:  2019-11-05       Impact factor: 4.615

Review 10.  A decade of individual participant data meta-analyses: A review of current practice.

Authors:  Mark Simmonds; Gavin Stewart; Lesley Stewart
Journal:  Contemp Clin Trials       Date:  2015-06-17       Impact factor: 2.226
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