Literature DB >> 345424

Pathogenicity in mice of strains of Candida albicans with different in vitro sensitivity to 5-fluorocytosine.

M Persson, B Winblad, S Anséhn, J Schönebeck.   

Abstract

The pathogenicity in mice of 7 strains of Candida albicans with different in vitro susceptibility to 5-fluorocytosine (5-FC) was investigated. Resistant strains were not less virulent than susceptible strains. This is contradictory to findings reported for candida strains resistant to polyene antibiotics, which were less pathogenic than susceptible strains. The implications of these findings are discussed.

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Year:  1978        PMID: 345424     DOI: 10.3109/inf.1978.10.issue-1.19

Source DB:  PubMed          Journal:  Scand J Infect Dis        ISSN: 0036-5548


  2 in total

Review 1.  Drug resistance in human pathogenic fungi.

Authors:  K Iwata
Journal:  Eur J Epidemiol       Date:  1992-05       Impact factor: 8.082

2.  Microtiter broth dilution method for yeast susceptibility testing with validation by clinical outcome.

Authors:  M Radetsky; R C Wheeler; M H Roe; J K Todd
Journal:  J Clin Microbiol       Date:  1986-10       Impact factor: 5.948

  2 in total

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