Literature DB >> 3453834

Approximate computation of probability functions for pedigree analysis.

A Thomas1.   

Abstract

Approximation by factorization of R functions is considered as a way of making the peeling method for calculation of probability functions more efficient and applicable to larger and more complex pedigrees. We show that, in some situations, the method is not approximate but a simplified way of calculating the true probability functions. The entropy function is used for a measure of the quality of factorization. The method is illustrated by an analysis of the origin of the B allele in the ABO blood type system on Tristan da Cunha.

Entities:  

Mesh:

Substances:

Year:  1986        PMID: 3453834     DOI: 10.1093/imammb/3.3.157

Source DB:  PubMed          Journal:  IMA J Math Appl Med Biol        ISSN: 0265-0746


  3 in total

1.  An approximation to the likelihood for a pedigree with loops.

Authors:  T Wang; R L Fernando; C Stricker; R C Elston
Journal:  Theor Appl Genet       Date:  1996-12       Impact factor: 5.699

2.  Markov chain Monte Carlo segregation and linkage analysis for oligogenic models.

Authors:  S C Heath
Journal:  Am J Hum Genet       Date:  1997-09       Impact factor: 11.025

3.  An efficient algorithm to compute marginal posterior genotype probabilities for every member of a pedigree with loops.

Authors:  Liviu R Totir; Rohan L Fernando; Joseph Abraham
Journal:  Genet Sel Evol       Date:  2009-12-03       Impact factor: 4.297

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.