Literature DB >> 34532653

Diagnostic Laboratories' Capacities and Preparedness for Emerging Viral Diseases in Guinea and Mali.

Tiffany Zhang Teng1, Abdoul Habib Beavogui2,3, Bassirou Diarra4, Alexandre Delamou2,3, Jane Holl5, Almoustapha Issiaka Maiga4, Yeya Dit Sadio Sarro4, Amadou Kone4, Bourahima Kone4, Djeneba Bocar Fofana4, Etienne Dembele1, Mamadou Saliou Sow6, Moussa Seydi7, Aboubacar Alassane Oumar4, Mahamadou Diakité4, Souleymane Diallo4, Seydou Doumbia4, Sounkalo Dao4, Robert L Murphy1, Mamoudou Maiga1,4.   

Abstract

The 2014-2016 Ebola epidemic in Guinea highlighted the need for more extensive evaluation of laboratories diagnostic capacities and preparedness in anticipation of future emerging viral disease outbreaks. We developed a questionnaire to assess the diagnostic capacities and preparedness of the four major medical laboratories in Guinea and Mali that are responsible for the provision of Ebola, Lassa, and Dengue diagnostics. The questionnaire inquired about the current state and need for equipment and reagents and adequacy of equipment and training received. In Guinea, all three diagnostic laboratories have the capacity and are well-prepared to perform Ebola diagnostics, however, only two have the capacity and trained staff to diagnose Lassa and none are currently prepared to diagnose Dengue infection. In Mali, the University Clinical Research Center (UCRC) laboratory, which was in charge of Ebola diagnostics during the last epidemic, currently has the capacity and is prepared to diagnose Ebola, Lassa, and Dengue infections. Combined, Guinea and Mali appear to have complementary capacity and preparedness to diagnose these Category A Priority Pathogens. While, the equipment, reagents and training efforts should be maintained, the gap in Dengue diagnostic capability in Guinea should be addressed with further equipping and training of additional district laboratories to strengthen the public health response for all viral diseases in these high-risk, yet, low-resource settings.

Entities:  

Keywords:  Diagnostic; Emerging Viral Diseases; Guinea; Mali; Preparedness

Year:  2020        PMID: 34532653      PMCID: PMC8442766     

Source DB:  PubMed          Journal:  Infect Dis Diagn Treat        ISSN: 2577-1515


  18 in total

1.  Diagnosis and clinical virology of Lassa fever as evaluated by enzyme-linked immunosorbent assay, indirect fluorescent-antibody test, and virus isolation.

Authors:  D G Bausch; P E Rollin; A H Demby; M Coulibaly; J Kanu; A S Conteh; K D Wagoner; L K McMullan; M D Bowen; C J Peters; T G Ksiazek
Journal:  J Clin Microbiol       Date:  2000-07       Impact factor: 5.948

Review 2.  Guidelines for Plaque-Reduction Neutralization Testing of Human Antibodies to Dengue Viruses.

Authors:  John T Roehrig; Joachim Hombach; Alan D T Barrett
Journal:  Viral Immunol       Date:  2008-06       Impact factor: 2.257

3.  Laboratory Response to 2014 Ebola Virus Outbreak in Mali.

Authors:  Bassirou Diarra; David Safronetz; Yeya Dit Sadio Sarro; Amadou Kone; Moumine Sanogo; Sady Tounkara; Antieme C G Togo; Fatoumata Daou; Almoustapha I Maiga; Sounkalo Dao; Kyle Rosenke; Darryl Falzarano; Seydou Doumbia; Kathryn C Zoon; Michael Polis; Sophia Siddiqui; Samba Sow; Tom G Schwan; Heinz Feldmann; Souleyman Diallo; Ousmane A Koita
Journal:  J Infect Dis       Date:  2016-10-15       Impact factor: 5.226

Review 4.  Overview, Control Strategies, and Lessons Learned in the CDC Response to the 2014-2016 Ebola Epidemic.

Authors:  Beth P Bell; Inger K Damon; Daniel B Jernigan; Thomas A Kenyon; Stuart T Nichol; John P O'Connor; Jordan W Tappero
Journal:  MMWR Suppl       Date:  2016-07-08

Review 5.  Variation in dengue virus plaque reduction neutralization testing: systematic review and pooled analysis.

Authors:  Kaitlin Rainwater-Lovett; Isabel Rodriguez-Barraquer; Derek A T Cummings; Justin Lessler
Journal:  BMC Infect Dis       Date:  2012-09-28       Impact factor: 3.090

6.  Dengue virus infection in Africa.

Authors:  Ananda Amarasinghe; Joel N Kuritsk; G William Letson; Harold S Margolis
Journal:  Emerg Infect Dis       Date:  2011-08       Impact factor: 6.883

7.  Imported Lassa fever: a report of 2 cases in Ghana.

Authors:  Nicholas N A Kyei; Mark M Abilba; Foster K Kwawu; Prince G Agbenohevi; Joseph H K Bonney; Thomas K Agbemaple; Shirley C Nimo-Paintsil; William Ampofo; Sally-Ann Ohene; Edward O Nyarko
Journal:  BMC Infect Dis       Date:  2015-05-29       Impact factor: 3.090

Review 8.  Towards detection and diagnosis of Ebola virus disease at point-of-care.

Authors:  Ajeet Kaushik; Sneham Tiwari; Rahul Dev Jayant; Aileen Marty; Madhavan Nair
Journal:  Biosens Bioelectron       Date:  2015-08-20       Impact factor: 10.618

Review 9.  Cationic host defense peptides; novel antimicrobial therapeutics against Category A pathogens and emerging infections.

Authors:  Fern Findlay; Lorna Proudfoot; Craig Stevens; Peter G Barlow
Journal:  Pathog Glob Health       Date:  2016-06-17       Impact factor: 2.894

10.  Risk maps of Lassa fever in West Africa.

Authors:  Elisabeth Fichet-Calvet; David John Rogers
Journal:  PLoS Negl Trop Dis       Date:  2009-03-03
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