Literature DB >> 34527625

Pulmonary Embolism in Autosomal Dominant Polycystic Kidney Patient Induced by Inferior Vena Cava Mechanical Compression.

Maamoun Basheer1, Elias Saad1,2, Nimer Assy1,2.   

Abstract

INTRODUCTION: Autosomal dominant polycystic kidney disease is a common syndrome. Renal and hepatic cysts can cause discomfort, bleeding, rupture, infection, hypertension and a mass effect with compression of adjacent organs. CASE
PRESENTATION: A 48-year-old man with polycystic kidney disease and hypertension presented to the emergency department for bilateral flank pain. An abdominal computed tomography scan with contrast showed a 7 cm heterogeneous process posteriorly and laterally to the right kidney. It appeared to be a renal cyst associated with bleeding and bilateral pulmonary artery filling defects, apparently due to pulmonary embolism. Cavography following inferior vena cava filter insertion did not show any deep vein thrombosis. DISCUSSION AND
CONCLUSION: The pulmonary embolism was probably caused by extrinsic inferior vena cava compression by a liver cyst. Virchow's triad of stasis, vessel damage and hypercoagulability probably resulted in a thrombus which moved on the right side to the pulmonary artery. LEARNING POINTS: Autosomal dominant polycystic kidney disease is a common syndrome.Renal and hepatic cysts can compress adjacent organs.The mass effect of a large cyst on the right side compressed the inferior vena cava, resulting in Virchow's triad of stasis, vessel damage and hypercoagulability, which can cause pulmonary embolism. © EFIM 2021.

Entities:  

Keywords:  Autosomal dominant polycystic kidney disease; inferior vena cava; pulmonary embolism; renal cyst

Year:  2021        PMID: 34527625      PMCID: PMC8436847          DOI: 10.12890/2021_002767

Source DB:  PubMed          Journal:  Eur J Case Rep Intern Med        ISSN: 2284-2594


  16 in total

Review 1.  Estimating prevalence in single-gene kidney diseases progressing to renal failure.

Authors:  M Levy; J Feingold
Journal:  Kidney Int       Date:  2000-09       Impact factor: 10.612

Review 2.  Autosomal dominant polycystic kidney disease.

Authors:  Vicente E Torres; Peter C Harris; Yves Pirson
Journal:  Lancet       Date:  2007-04-14       Impact factor: 79.321

3.  Acute pulmonary thromboembolism occurring during treatment with tolvaptan in a patient with autosomal-dominant polycystic kidney disease.

Authors:  Katsuhiko Morimoto; Yasuhiro Akai; Masaru Matsui; Hiroki Yano; Miho Tagawa; Ken-Ichi Samejima; Yoshihiko Saito
Journal:  CEN Case Rep       Date:  2017-01-24

Review 4.  Sudden death of a patient with polycystic kidneys due to acute inferior vena cava thrombosis.

Authors:  Riccardo Tamburrini; Zubir Ahmed; Jon van der Walt; David Goldsmith
Journal:  Scott Med J       Date:  2015-01-28       Impact factor: 0.729

Review 5.  Autosomal dominant polycystic kidney disease.

Authors:  P A Gabow
Journal:  N Engl J Med       Date:  1993-07-29       Impact factor: 91.245

6.  [Massive inferior vena cava thrombosis in a patient with autosomal dominant polycystic hepatorenal disease].

Authors:  R Peces; F Gil; O Costero; A Pobes
Journal:  Nefrologia       Date:  2002       Impact factor: 2.033

7.  [Deep Vein Thrombosis Due to Compression of Huge Hepatic Cyst Successfully Treated by Inferior Vena Cava Filter and Cyst Drainage].

Authors:  Myung Kwan Ko; Taehong Kim; Won Hyuk Lee; Seung Ha Park; Joon Hyuk Choi; Minwoo Shin; Nae Yun Heo
Journal:  Korean J Gastroenterol       Date:  2018-09-25

8.  Perinephric hemorrhage in autosomal dominant polycystic kidney disease: CT and MR findings.

Authors:  E Levine; J J Grantham
Journal:  J Comput Assist Tomogr       Date:  1987 Jan-Feb       Impact factor: 1.826

9.  Thrombosis in inferior vena cava (IVC) due to intra-cystic hemorrhage into a hepatic local cyst with autosomal dominant polycystic kidney disease (ADPKD).

Authors:  Seitaro Iguchi; Akio Kasai; Hidefumi Kishimoto; Kazuo Suzuki; Satoshi Ito; Yusuke Ogawa; Shinichi Nishi; Fumitake Gejyo; Yasuhiko Ohno
Journal:  Intern Med       Date:  2004-03       Impact factor: 1.271

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  1 in total

1.  Recurrent thromboses and major vessel compressions in autosomal dominant polycystic kidney disease.

Authors:  Joel Ern Zher Chan; Zhihong Kuah; Shantanu Bhattacharjya; Santosh Antony Olakkengil
Journal:  J Surg Case Rep       Date:  2022-02-13
  1 in total

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