Yu Wu1, Ying Liu2, Tao Huang1, Yasu Jiang3, Hua Wang1, Zhixian He1. 1. Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, China. 2. Department of General Surgery, Nantong Geriatric Rehabilitation Hospital, Nantong, China. 3. Department of General Surgery, the Second Affiliated Hospital of Nantong University, Nantong, China.
Abstract
BACKGROUND: Our objective is to evaluate the application values and effects of nanocarbon negative imaging technology in surgery for patients with the fifth stage of chronic kidney disease complicated with secondary hyperparathyroidism (SHPT). METHODS: Eighty-nine patients with SHPT in the fifth stage of chronic kidney disease admitted to the Department of Thyroid and Breast Surgery at the Affiliated Hospital of Nantong University between January 2018 and August 2020 were selected. All patients underwent total parathyroidectomy (tPTX) and were randomly divided into a group receiving nanocarbon (observation group; group A) and a control group (group B). Patients were followed up for 6 months after surgery and several observation indexes were compared and analyzed. RESULTS: Compared with the control group, the parathyroid glands in the observation group treated with nanocarbon were more clearly exposed, and better performances were seen in the operation time, blood loss, and recovery rate of bone pain (P<0.05). The postoperative follow-up blood intact parathyroid hormone level (iPTH) and recurrence rate control were also improved in the observation group and the differences were statistically significant (P<0.05). CONCLUSIONS: In the fifth stage of chronic kidney disease with SHPT, the application of nanocarbon negative imaging technology can significantly reduce the recurrence rate of hyperparathyroidism, improve the surgical effect, and improve the long-term quality of life and survival rate of patients. 2021 Gland Surgery. All rights reserved.
BACKGROUND: Our objective is to evaluate the application values and effects of nanocarbon negative imaging technology in surgery for patients with the fifth stage of chronic kidney disease complicated with secondary hyperparathyroidism (SHPT). METHODS: Eighty-nine patients with SHPT in the fifth stage of chronic kidney disease admitted to the Department of Thyroid and Breast Surgery at the Affiliated Hospital of Nantong University between January 2018 and August 2020 were selected. All patients underwent total parathyroidectomy (tPTX) and were randomly divided into a group receiving nanocarbon (observation group; group A) and a control group (group B). Patients were followed up for 6 months after surgery and several observation indexes were compared and analyzed. RESULTS: Compared with the control group, the parathyroid glands in the observation group treated with nanocarbon were more clearly exposed, and better performances were seen in the operation time, blood loss, and recovery rate of bone pain (P<0.05). The postoperative follow-up blood intact parathyroid hormone level (iPTH) and recurrence rate control were also improved in the observation group and the differences were statistically significant (P<0.05). CONCLUSIONS: In the fifth stage of chronic kidney disease with SHPT, the application of nanocarbon negative imaging technology can significantly reduce the recurrence rate of hyperparathyroidism, improve the surgical effect, and improve the long-term quality of life and survival rate of patients. 2021 Gland Surgery. All rights reserved.
Entities:
Keywords:
Nanocarbon; secondary hyperparathyroidism (SHPT); total parathyroidectomy (tPTX)
Authors: Tamara Isakova; Thomas L Nickolas; Michelle Denburg; Sri Yarlagadda; Daniel E Weiner; Orlando M Gutiérrez; Vinod Bansal; Sylvia E Rosas; Sagar Nigwekar; Jerry Yee; Holly Kramer Journal: Am J Kidney Dis Date: 2017-09-21 Impact factor: 8.860
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