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Literature DB >> 34511185

Pathology and Molecular Characteristics of Pancreatic Cancer.

Joseph F Kearney¹, Volkan Adsay², Jen Jen Yeh³.

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer. However, it should be kept in mind that there are other pancreatic cancers that are classified by their cellular lineage: acinar cell carcinomas (acinar differentiation), neuroendocrine neoplasms (arising from the islets), solid-pseudopapillary neoplasms (showing no discernible cell lineage), and pancreatoblastomas (characterized by multiphenotypic differentiation, including acinar endocrine and ductal). This article focuses on the molecular and pathology alterations in PDAC.

Entities: Chemical

Keywords: Pancreatic cancer; Pancreatic ductal adenocarcinoma; Tumor microenvironment

Mesh：

Year: 2021 PMID： 34511185 PMCID： PMC8442745 DOI： 10.1016/j.soc.2021.06.003

Source DB: PubMed Journal: Surg Oncol Clin N Am ISSN： 1055-3207 Impact factor: 2.402

70 in total

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5. Frequency and clinicopathologic associations of DNA mismatch repair protein deficiency in ampullary carcinoma: Routine testing is indicated.

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Journal: Cancer Date: 2020-08-28 Impact factor: 6.860

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Journal: Nat Commun Date: 2017-07-07 Impact factor: 14.919

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Journal: Nat Rev Cancer Date: 2020-01-24 Impact factor: 60.716

8. Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes.

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Journal: Nat Commun Date: 2018-05-17 Impact factor: 14.919

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10. Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation.

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1 in total

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