Literature DB >> 34507929

Severe hypertension in pregnancy.

Kate Wiles1, Mellisa Damodaram2, Charlotte Frise3.   

Abstract

Severe hypertension in pregnancy is defined as a sustained systolic blood pressure of 160 mmHg or over or diastolic blood pressure of 110 mmHg or over and should be assessed in hospital. Severe hypertension before 20 weeks' gestation is rare and usually due to chronic hypertension; assessment for target organ damage and exclusion of secondary hypertension are warranted. The most common cause of severe hypertension in pregnancy is pre-eclampsia, which presents after 20 weeks' gestation. This warrants more rapid control of blood pressure due to the risk of haemorrhagic stroke, and intravenous antihypertensive agents may be required. Treatment is determined by licensing, availability and clinician experience, with no high-level evidence to guide prescribing. Labetalol is the agent most commonly used, both orally and intravenously, in pregnancy in the UK. Severe hypertension is a risk factor for sustained hypertension after pregnancy. Hypertension in pregnancy is associated with increased cardiovascular risk. © Royal College of Physicians 2021. All rights reserved.

Entities:  

Keywords:  hypertension; pre-eclampsia; pregnancy

Mesh:

Substances:

Year:  2021        PMID: 34507929      PMCID: PMC8439512          DOI: 10.7861/clinmed.2021-0508

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   5.410


  17 in total

1.  Adverse perinatal outcomes are significantly higher in severe gestational hypertension than in mild preeclampsia.

Authors:  Alan Buchbinder; Baha M Sibai; Steve Caritis; Cora Macpherson; John Hauth; Marshall D Lindheimer; Mark Klebanoff; Peter Vandorsten; Mark Landon; Richard Paul; Menachem Miodovnik; Paul Meis; Gary Thurnau
Journal:  Am J Obstet Gynecol       Date:  2002-01       Impact factor: 8.661

2.  The excretion of enalapril and enalaprilat in human breast milk.

Authors:  C W Redman; J G Kelly; W D Cooper
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

3.  Gestation-Specific Vital Sign Reference Ranges in Pregnancy.

Authors:  Lauren J Green; Lucy H Mackillop; Dario Salvi; Rebecca Pullon; Lise Loerup; Lionel Tarassenko; Jude Mossop; Clare Edwards; Stephen Gerry; Jacqueline Birks; Rupert Gauntlett; Kate Harding; Lucy C Chappell; Peter J Watkinson
Journal:  Obstet Gynecol       Date:  2020-03       Impact factor: 7.661

4.  Preeclampsia and ESRD: The Role of Shared Risk Factors.

Authors:  Andrea G Kattah; Dawn C Scantlebury; Sanket Agarwal; Michelle M Mielke; Walter A Rocca; Amy L Weaver; Lisa E Vaughan; Virginia M Miller; Tracey L Weissgerber; Wendy White; Vesna D Garovic
Journal:  Am J Kidney Dis       Date:  2016-10-01       Impact factor: 8.860

5.  Diagnosis and management of hypertension in pregnancy: summary of updated NICE guidance.

Authors:  Katie Webster; Sarah Fishburn; Mike Maresh; Sarah C Findlay; Lucy C Chappell
Journal:  BMJ       Date:  2019-09-09

6.  Clinical practice guideline on pregnancy and renal disease.

Authors:  Kate Wiles; Lucy Chappell; Katherine Clark; Louise Elman; Matt Hall; Liz Lightstone; Germin Mohamed; Durba Mukherjee; Catherine Nelson-Piercy; Philip Webster; Rebecca Whybrow; Kate Bramham
Journal:  BMC Nephrol       Date:  2019-10-31       Impact factor: 2.388

7.  Postpartum management of hypertension.

Authors:  Kate Bramham; Catherine Nelson-Piercy; Morris J Brown; Lucy C Chappell
Journal:  BMJ       Date:  2013-02-25

Review 8.  Proteinuria during pregnancy: definition, pathophysiology, methodology, and clinical significance.

Authors:  Michal Fishel Bartal; Marshall D Lindheimer; Baha M Sibai
Journal:  Am J Obstet Gynecol       Date:  2020-09-01       Impact factor: 8.661

9.  Antihypertensive drug therapy for mild to moderate hypertension during pregnancy.

Authors:  Edgardo Abalos; Lelia Duley; D Wilhelm Steyn; Celina Gialdini
Journal:  Cochrane Database Syst Rev       Date:  2018-10-01

10.  The CHIPS Randomized Controlled Trial (Control of Hypertension in Pregnancy Study): Is Severe Hypertension Just an Elevated Blood Pressure?

Authors:  Laura A Magee; Peter von Dadelszen; Joel Singer; Terry Lee; Evelyne Rey; Susan Ross; Elizabeth Asztalos; Kellie E Murphy; Jennifer Menzies; Johanna Sanchez; Amiram Gafni; Michael Helewa; Eileen Hutton; Gideon Koren; Shoo K Lee; Alexander G Logan; Wessel Ganzevoort; Ross Welch; Jim G Thornton; Jean-Marie Moutquin
Journal:  Hypertension       Date:  2016-09-12       Impact factor: 10.190

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  3 in total

1.  The differential diagnosis of pre-eclampsia should include the association of severe hypertension and aortic dissection.

Authors:  Oscar Jolobe
Journal:  Clin Med (Lond)       Date:  2022-01       Impact factor: 2.659

2.  In response to crisis, is versatility a reward or a necessity.

Authors:  Anton Emmanuel
Journal:  Clin Med (Lond)       Date:  2021-09       Impact factor: 5.410

3.  Urinary Protein-to-Creatinine Ratio: An Indicator of Adverse Clinical Outcomes in Preeclampsia With Proteinuria.

Authors:  Arzoo Chadha; Surekha Tayade
Journal:  Cureus       Date:  2022-03-20
  3 in total

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