Disposition of vancomycin in healthy volunteers from oral solution and semi-solid matrix capsules.

Gastrointestinal availability of vancomycin from oral solution and semi-solid matrix capsules was determined in volunteers. The capsule produced faecal, plasma and urine levels of the antibiotic which are similar to those obtained with the solution and offers a viable, convenient oral dosage form.

RCT Entities:   Population Interventions Outcomes