Literature DB >> 34486396

Targeting Parasympathetic Activity to Improve Autonomic Tone and Clinical Outcomes.

Matthew W Kay1, Vivek Jain2, Gurusher Panjrath3, David Mendelowitz4.   

Abstract

In this review we will briefly summarize the evidence that autonomic imbalance, more specifically reduced parasympathetic activity to the heart, generates and/or maintains many cardiorespiratory diseases and will discuss mechanisms and sites, from myocytes to the brain, that are potential translational targets for restoring parasympathetic activity and improving cardiorespiratory health.

Entities:  

Keywords:  OSA; autonomic; cardiac; heart failure; parasympathetic

Mesh:

Year:  2021        PMID: 34486396      PMCID: PMC8742722          DOI: 10.1152/physiol.00023.2021

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN: 1548-9221


  87 in total

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2.  Neurotransmission to parasympathetic cardiac vagal neurons in the brain stem is altered with left ventricular hypertrophy-induced heart failure.

Authors:  Edmund Cauley; Xin Wang; Jhansi Dyavanapalli; Ke Sun; Kara Garrott; Sarah Kuzmiak-Glancy; Matthew W Kay; David Mendelowitz
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Journal:  Am J Physiol Heart Circ Physiol       Date:  2007-03-23       Impact factor: 4.733

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Authors:  Gisele L Cavalcante; Fernanda Brognara; Lucas Vaz de C Oliveira; Renata M Lataro; Marina de T Durand; Aldeidia P de Oliveira; Antônio Cláudio L da Nóbrega; Helio C Salgado; João Paulo J Sabino
Journal:  Acta Physiol (Oxf)       Date:  2021-04-21       Impact factor: 6.311

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Authors:  A Selcuk Adabag; Terry M Therneau; Bernard J Gersh; Susan A Weston; Véronique L Roger
Journal:  JAMA       Date:  2008-11-05       Impact factor: 56.272

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Journal:  Br Med J       Date:  1972-07-08

Review 8.  The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective.

Authors:  Syed S Mahmood; Daniel Levy; Ramachandran S Vasan; Thomas J Wang
Journal:  Lancet       Date:  2013-09-29       Impact factor: 79.321

9.  Chronic activation of hypothalamic oxytocin neurons improves cardiac function during left ventricular hypertrophy-induced heart failure.

Authors:  Kara Garrott; Jhansi Dyavanapalli; Edmund Cauley; Mary Kate Dwyer; Sarah Kuzmiak-Glancy; Xin Wang; David Mendelowitz; Matthew W Kay
Journal:  Cardiovasc Res       Date:  2017-09-01       Impact factor: 10.787

10.  Innervation and Neuronal Control of the Mammalian Sinoatrial Node a Comprehensive Atlas.

Authors:  Peter Hanna; Michael J Dacey; Jaclyn Brennan; Alison Moss; Shaina Robbins; Sirisha Achanta; Natalia P Biscola; Mohammed A Swid; Pradeep S Rajendran; Shumpei Mori; Joseph E Hadaya; Elizabeth H Smith; Stanley G Peirce; Jin Chen; Leif A Havton; Zixi Jack Cheng; Rajanikanth Vadigepalli; James Schwaber; Robert L Lux; Igor Efimov; John D Tompkins; Donald B Hoover; Jeffrey L Ardell; Kalyanam Shivkumar
Journal:  Circ Res       Date:  2021-02-25       Impact factor: 17.367

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