Literature DB >> 34479020

Nanotechnology-based drug delivery for central nervous system disorders.

Thuy Trang Nguyen1, Thi Thuy Dung Nguyen2, Tuong Kha Vo3, Nguyen-Minh-An Tran4, Minh Kim Nguyen5, Toi Van Vo6, Giau Van Vo7.   

Abstract

Drug delivery to central nervous system (CNS) diseases is very challenging since the presence of the innate blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier that impede drug delivery. Among new strategies to overcome these limitations and successfully deliver drugs to the CNS, nanotechnology-based drug delivery platform, offers potential therapeutic approach for the treatment of some common neurological disorders like Alzheimer's disease, frontotemporal dementia, amyotrophic lateral sclerosis, Parkinson's disease, Huntington's disease. This review aimed to highlight advances in research on the development of nano-based therapeutics for their implications in therapy of CNS disorders. The challenges during clinical translation of nanomedicine from bench to bed side is also discussed.
Copyright © 2021 The Authors. Published by Elsevier Masson SAS.. All rights reserved.

Entities:  

Keywords:  CNS; Molecular targets; Nanomedicine; Nanoparticles; Oxidative stress

Mesh：

Substances：

Year:  2021        PMID： 34479020     DOI： 10.1016/j.biopha.2021.112117

Source DB:  PubMed          Journal:  Biomed Pharmacother        ISSN： 0753-3322            Impact factor:   6.529


  7 in total

Review 1.  Advances in Hydrogel-Based Drug Delivery Systems for Parkinson's Disease.

Authors:  Thuy Trang Nguyen; Nguyen Si Bao; Giau Van Vo
Journal:  Neurochem Res       Date:  2022-05-20       Impact factor: 4.414

Review 2.  Applications of Various Types of Nanomaterials for the Treatment of Neurological Disorders.

Authors:  Abdul Waris; Asmat Ali; Atta Ullah Khan; Muhammad Asim; Doaa Zamel; Kinza Fatima; Abdur Raziq; Muhammad Ajmal Khan; Nazia Akbar; Abdul Baset; Mohammed A S Abourehab
Journal:  Nanomaterials (Basel)       Date:  2022-06-22       Impact factor: 5.719

Review 3.  Crosstalk Between Intestinal Serotonergic System and Pattern Recognition Receptors on the Microbiota-Gut-Brain Axis.

Authors:  Elena Layunta; Berta Buey; Jose Emilio Mesonero; Eva Latorre
Journal:  Front Endocrinol (Lausanne)       Date:  2021-11-08       Impact factor: 5.555

Review 4.  Advances on Therapeutic Strategies for Alzheimer's Disease: From Medicinal Plant to Nanotechnology.

Authors:  Nasser A Hassan; Asma K Alshamari; Allam A Hassan; Mohamed G Elharrif; Abdullah M Alhajri; Mohammed Sattam; Reham R Khattab
Journal:  Molecules       Date:  2022-07-28       Impact factor: 4.927

Review 5.  Nanotechnology-Based Combinatorial Anti-Glioblastoma Therapies: Moving from Terminal to Treatable.

Authors:  Amir Barzegar Behrooz; Zahra Talaie; Amir Syahir
Journal:  Pharmaceutics       Date:  2022-08-15       Impact factor: 6.525

6.  Assessing cellular internalization and endosomal escape abilities of novel BUFII-Graphene oxide nanobioconjugates.

Authors:  Julian Daniel Torres-Vanegas; Javier Cifuentes; Paola Ruiz Puentes; Valentina Quezada; Andres J Garcia-Brand; Juan C Cruz; Luis H Reyes
Journal:  Front Chem       Date:  2022-09-15       Impact factor: 5.545

Review 7.  A New Perspective on the Treatment of Alzheimer's Disease and Sleep Deprivation-Related Consequences: Can Curcumin Help?

Authors:  Esra Küpeli Akkol; Hilal Bardakcı; Çiğdem Yücel; Gökçe Şeker Karatoprak; Büşra Karpuz; Haroon Khan
Journal:  Oxid Med Cell Longev       Date:  2022-01-12       Impact factor: 7.310
  7 in total

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