Literature DB >> 3447898

Diagnosing the tight building syndrome.

S A Rogers1.   

Abstract

Formaldehyde is but one of many chemicals capable of causing the tight building syndrome or environmentally induced illness (EI). The spectrum of symptoms it may induce includes attacks of headache, flushing, laryngitis, dizziness, nausea, extreme weakness, arthralgia, unwarranted depression, dysphonia, exhaustion, inability to think clearly, arrhythmia or muscle spasms. The nonspecificity of such symptoms can baffle physicians from many specialties. Presented herein is a simple office method for demonstrating that formaldehyde is among the etiologic agents triggering these symptoms. The very symptoms that patients complain of can be provoked within minutes, and subsequently abolished, with an intradermal injection of the appropriate strength of formaldehyde. This injection aids in convincing the patient of the cause of the symptoms so he can initiate measures to bring his disease under control.

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Year:  1987        PMID: 3447898      PMCID: PMC1474484          DOI: 10.1289/ehp.8776195

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  12 in total

1.  Studies on methanol toxicity and formate metabolism in isolated hepatocytes. The role of methionine in folate-dependent reactions.

Authors:  R E Billings; T R Tephly
Journal:  Biochem Pharmacol       Date:  1979-10-01       Impact factor: 5.858

Review 2.  Allergic reactions to industrial chemicals.

Authors:  K G McGrath; C R Zeiss; R Patterson
Journal:  Clin Immunol Rev       Date:  1983

3.  The sick building syndrome: prevalence studies.

Authors:  M J Finnegan; C A Pickering; P S Burge
Journal:  Br Med J (Clin Res Ed)       Date:  1984-12-08

Review 4.  Neuropsychological effects of industrial toxins: a review.

Authors:  R G Feldman; N L Ricks; E L Baker
Journal:  Am J Ind Med       Date:  1980       Impact factor: 2.214

5.  Alteration of induced cellular and humoral immune responses by pesticides and chemicals of environmental concern: quantitative studies of immunosuppression by DDT, aroclor 1254, carbaryl, carbofuran, and methylparathion.

Authors:  J C Street; R P Sharma
Journal:  Toxicol Appl Pharmacol       Date:  1975-06       Impact factor: 4.219

6.  Cleavage of the third complement component (C3) and generation of the spasmogenic peptide, C3a, in human serum via the properdin pathway: demonstration of inhibitory as well as enhancing effects of epsilon-amino-caproic acid.

Authors:  W Vogt; G Schmidt; R Lynen; L Dieminger
Journal:  J Immunol       Date:  1975-02       Impact factor: 5.422

7.  Hyperosmolar triggering of histamine release from human basophils.

Authors:  S R Findlay; A M Dvorak; A Kagey-Sobotka; L M Lichtenstein
Journal:  J Clin Invest       Date:  1981-06       Impact factor: 14.808

8.  Environmentally triggered cardiac disease.

Authors:  W J Rea
Journal:  Ann Allergy       Date:  1978-04

9.  Formaldehyde exposure in nonoccupational environments.

Authors:  K A Dally; L P Hanrahan; M A Woodbury; M S Kanarek
Journal:  Arch Environ Health       Date:  1981 Nov-Dec

10.  Mechanisms of chemical toxicity--a unifying hypothesis.

Authors:  D V Parke
Journal:  Regul Toxicol Pharmacol       Date:  1982-12       Impact factor: 3.271

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