Literature DB >> 34478641

Tumor organoid-originated biomarkers predict immune response to PD-1 blockade.

Cansu Cimen Bozkus1, Nina Bhardwaj2.   

Abstract

Despite the demonstrated efficacy and broad applicability of checkpoint blockade, the mechanisms by which it exerts its antitumor effects are incompletely understood. A recent article in Nature Medicine describes an ex vivo platform for assessing early responses to checkpoint blockade and the properties of tumor immune contexture in correlation to clinical responses.
Copyright © 2021 Elsevier Inc. All rights reserved.

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Year:  2021        PMID: 34478641     DOI: 10.1016/j.ccell.2021.08.003

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  1 in total

1.  Editorial: Recent 3D Tumor Models for Testing Immune-Mediated Therapies.

Authors:  Jacques Zimmer; Roberta Castriconi; Silvia Scaglione
Journal:  Front Immunol       Date:  2021-11-18       Impact factor: 7.561

  1 in total

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