Literature DB >> 34477886

Effects of stimulant medication on divergent and convergent thinking tasks related to creativity in adults with attention-deficit hyperactivity disorder.

Molly McBride1, Carrina Appling2, Bradley Ferguson2,3,4, Alyssia Gonzalez5, Andrea Schaeffer1, Amanda Zand1, David Wang6, Alinna Sam1, Eric Hart4, Aneesh Tosh7, Ivan Fontcha8, Sophia Parmacek9, David Beversdorf10,11,12,13,14.   

Abstract

RATIONALE: Common pharmacological treatments for attention-deficit hyperactivity disorder (ADHD) are central nervous system stimulants acting as norepinephrine-dopamine reuptake inhibitors. The noradrenergic and dopaminergic systems have been shown to impact performance on tasks assessing creativity. Some previous studies suggest higher performance on creativity tasks in ADHD. Stimulant medication has been shown to differentially impact creativity in those without ADHD. However, the full range of effects of stimulant medication on creativity in those with ADHD is not known.
OBJECTIVES: This study examined the effects of stimulants on convergent and divergent tasks associated with creativity in adults with ADHD.
METHOD: Seventeen adults diagnosed with ADHD who were prescribed stimulant medication attended two counterbalanced sessions: one after taking their prescribed stimulant dose and one after the dose was withheld. Participants completed convergent problem-solving (anagrams, Compound Remote Associates) and divergent generative (letter/semantic fluency, Torrance Test for Creative Thinking (TTCT)-Verbal) tasks.
RESULTS: There was a significant increase in words generated on the semantic fluency task for the stimulant session. Additionally, significant increases were found in the stimulant session for originality, flexibility, and fluency scores on the TTCT. Stimulant medication did not have an effect on any of the problem-solving tasks.
CONCLUSIONS: Stimulant medication enhanced verbal fluency in adults with ADHD but had no effect on convergent abilities. Furthermore, stimulants enhanced fluency, flexibility, and originality scores on the TTCT. Therefore, stimulants appear to have positive effects on divergent task performance in adults with ADHD, but not convergent tasks. This finding warrants further studies into the specific roles of norepinephrine and dopamine in this effect.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Attention-deficit hyperactivity disorder; Creativity; Dopamine; Norepinephrine; Stimulant medication

Mesh:

Substances:

Year:  2021        PMID: 34477886     DOI: 10.1007/s00213-021-05970-0

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  29 in total

1.  Normative data for 144 compound remote associate problems.

Authors:  Edward M Bowden; Mark Jung-Beeman
Journal:  Behav Res Methods Instrum Comput       Date:  2003-11

2.  The (b)link between creativity and dopamine: spontaneous eye blink rates predict and dissociate divergent and convergent thinking.

Authors:  Soghra Akbari Chermahini; Bernhard Hommel
Journal:  Cognition       Date:  2010-03-23

Review 3.  An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance.

Authors:  Gary Aston-Jones; Jonathan D Cohen
Journal:  Annu Rev Neurosci       Date:  2005       Impact factor: 12.449

4.  Beta-adrenergic modulation of cognitive flexibility during stress.

Authors:  Jessica K Alexander; Ashleigh Hillier; Ryan M Smith; Madalina E Tivarus; David Q Beversdorf
Journal:  J Cogn Neurosci       Date:  2007-03       Impact factor: 3.225

5.  Increased task difficulty results in greater impact of noradrenergic modulation of cognitive flexibility.

Authors:  Heather L Campbell; Madalina E Tivarus; Ashleigh Hillier; David Q Beversdorf
Journal:  Pharmacol Biochem Behav       Date:  2007-08-19       Impact factor: 3.533

6.  Neuropsychopharmacological regulation of performance on creativity-related tasks.

Authors:  David Q Beversdorf
Journal:  Curr Opin Behav Sci       Date:  2018-09-27

7.  In their own words: adolescent views on ADHD and their evolving role managing medication.

Authors:  William B Brinkman; Susan N Sherman; April R Zmitrovich; Marty O Visscher; Lori E Crosby; Kieran J Phelan; Edward F Donovan
Journal:  Acad Pediatr       Date:  2011-11-30       Impact factor: 3.107

Review 8.  The roles of dopamine and noradrenaline in the pathophysiology and treatment of attention-deficit/hyperactivity disorder.

Authors:  Natalia Del Campo; Samuel R Chamberlain; Barbara J Sahakian; Trevor W Robbins
Journal:  Biol Psychiatry       Date:  2011-05-06       Impact factor: 13.382

9.  Attenuated Tonic and Enhanced Phasic Release of Dopamine in Attention Deficit Hyperactivity Disorder.

Authors:  Rajendra D Badgaiyan; Sampada Sinha; Munawwar Sajjad; David S Wack
Journal:  PLoS One       Date:  2015-09-30       Impact factor: 3.240

10.  Creativity in ADHD: Goal-Directed Motivation and Domain Specificity.

Authors:  Nathalie Boot; Barbara Nevicka; Matthijs Baas
Journal:  J Atten Disord       Date:  2017-08-28       Impact factor: 3.256

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