Literature DB >> 3447334

A prospective, randomized study of 5-fluorouracil and filtration surgery.

J M Ruderman1, D B Welch, M F Smith, D E Shoch.   

Abstract

Our study shows that use of a small dose of subconjunctival 5-FU provides significantly lower postoperative intraocular pressure than does no antimetabolite treatment. Morphology of the postoperative blebs suggests that increased filtration results in lower intraocular pressure in the 5-FU group. Corneal epithelial defects were as common with a low dose as with higher doses previously described.

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Year:  1987        PMID: 3447334      PMCID: PMC1298776     

Source DB:  PubMed          Journal:  Trans Am Ophthalmol Soc        ISSN: 0065-9533


  11 in total

1.  Scleral Cautery with Iridectomy-An Experimental Study.

Authors:  E F Regan
Journal:  Trans Am Ophthalmol Soc       Date:  1963

2.  A modified filtering operation for neovascular glaucoma.

Authors:  J Herschler; D Agness
Journal:  Arch Ophthalmol       Date:  1979-12

3.  Trabecular surgery.

Authors:  A L Schwartz; D R Anderson
Journal:  Arch Ophthalmol       Date:  1974-08

4.  Filtration surgery in the treatment of neovascular glaucoma.

Authors:  R C Allen; A R Bellows; B T Hutchinson; S D Murphy
Journal:  Ophthalmology       Date:  1982-10       Impact factor: 12.079

5.  Structural and functional effects of trabeculectomy in cynomolgus monkeys. I. Light microscopy.

Authors:  E H Bäräny; E Linnër; E Lütjen-Drecoll; J W Rohen
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1972

6.  Trabeculectomy in young patients.

Authors:  M G Gressel; D K Heuer; R K Parrish
Journal:  Ophthalmology       Date:  1984-10       Impact factor: 12.079

7.  5-fluorouracil and glaucoma filtering surgery: I. An animal model.

Authors:  M G Gressel; R K Parrish; R Folberg
Journal:  Ophthalmology       Date:  1984-04       Impact factor: 12.079

8.  Serious corneal complications of glaucoma filtering surgery with postoperative 5-fluorouracil.

Authors:  A Knapp; D K Heuer; G A Stern; W T Driebe
Journal:  Am J Ophthalmol       Date:  1987-02-15       Impact factor: 5.258

9.  Surgical management of chronic glaucoma in aphakia.

Authors:  A R Bellows; M A Johnstone
Journal:  Ophthalmology       Date:  1983-07       Impact factor: 12.079

10.  5-Fluorouracil and glaucoma filtering surgery. III. Intermediate follow-up of a pilot study.

Authors:  D K Heuer; R K Parrish; M G Gressel; E Hodapp; D C Desjardins; G L Skuta; P F Palmberg; J A Nevárez; E J Rockwood
Journal:  Ophthalmology       Date:  1986-12       Impact factor: 12.079

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  2 in total

1.  A new delivery system for 5-fluorouracil using prodrug and converting enzyme.

Authors:  M Akimoto; T Miyahara; J Arai; A Akimoto; H Hamada; Y Yoshida; N Yoshimura
Journal:  Br J Ophthalmol       Date:  2002-05       Impact factor: 4.638

Review 2.  Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery.

Authors:  Emily Cabourne; Jonathan C K Clarke; Patricio G Schlottmann; Jennifer R Evans
Journal:  Cochrane Database Syst Rev       Date:  2015-11-06
  2 in total

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