Literature DB >> 34473326

Evaluation of Anti-Hepatocellular-Cancer Properties of β-Sitosterol and β-Sitosterol-Glucoside from Indigofera zollingeriana Miq.

Giau Van Vo1,2, Paul C Guest3, Thuy Trang Nguyen4, Tuong Kha Vo5.   

Abstract

Liver cancer is the most frequent cancer, making it the leading cause of cancer death globally. Traditional medicinal plants with anticancer properties can be used as drugs or dietary adjuvants to existing therapies. This chapter presents a protocol for the preparation of β-sitosterol and β-sitosterol-glucoside from Indigofera zollingeriana Miq (I. zollingeriana) and the evaluation of these for anticancer activity in hepatocellular cells.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Anticancer; HepG2; Huh7; Indigofera zollingeriana Miq; β-sitosterol; β-sitosterol-glucoside

Mesh：

Substances：

Year:  2022        PMID： 34473326     DOI： 10.1007/978-1-0716-1558-4_15

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  6 in total

1.  Anti-inflammatory and analgesic activities of ethanolic extract of Sphaeranthus indicus Linn.

Authors:  Adam Ali; Syed Baqir Shyum Naqvi; Shahnaz Gauhar; Rehana Saeed
Journal:  Pak J Pharm Sci       Date:  2011-07       Impact factor: 0.684

2.  beta-Sitosterol inhibits HT-29 human colon cancer cell growth and alters membrane lipids.

Authors:  A B Awad; Y C Chen; C S Fink; T Hennessey
Journal:  Anticancer Res       Date:  1996 Sep-Oct       Impact factor: 2.480

3.  Beta-sitosterol, a plant sterol, induces apoptosis and activates key caspases in MDA-MB-231 human breast cancer cells.

Authors:  Atif B Awad; Rajat Roy; Carol S Fink
Journal:  Oncol Rep       Date:  2003 Mar-Apr       Impact factor: 3.906

Review 4.  The National Cancer Institute: cancer drug discovery and development program.

Authors:  M R Grever; S A Schepartz; B A Chabner
Journal:  Semin Oncol       Date:  1992-12       Impact factor: 4.929

5.  Induction of Bax and activation of caspases during beta-sitosterol-mediated apoptosis in human colon cancer cells.

Authors:  Yung Hyun Choi; Kyu Ri Kong; Young-Ae Kim; Keun-Ok Jung; Jeong-Ha Kil; Sook-Hee Rhee; Kun-Young Park
Journal:  Int J Oncol       Date:  2003-12       Impact factor: 5.650

6.  Antimicrobial and Antioxidant Activities of Natural Compounds.

Authors:  Letizia Angiolella; Gianni Sacchetti; Thomas Efferth
Journal:  Evid Based Complement Alternat Med       Date:  2018-06-06       Impact factor: 2.629
  6 in total

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