Literature DB >> 3447125

Flupirtine--a new centrally acting analgesic with unique chemical structure.

J Engel1.   

Abstract

Flupirtine has a different structure from existing analgesics. Based on 3-dimensional structure data and molecular graphics experiments we can predict that flupirtine will not bind to opiate receptors because of structural differences from those of morphine.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3447125

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  2 in total

1.  Possible involvement of noradrenergic descending pain-modulating pathways in the mode of antinociceptive action of flupirtine, a novel non-opioid analgesic.

Authors:  B Nickel; J Engel; I Szelenyi
Journal:  Agents Actions       Date:  1988-02

2.  Mode of antinociceptive action of flupirtine in the rat.

Authors:  I Szelenyi; B Nickel; H O Borbe; K Brune
Journal:  Br J Pharmacol       Date:  1989-07       Impact factor: 8.739
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.