| Literature DB >> 34466132 |
Eric R Pedersen1, Jordan P Davis2, Reagan E Fitzke1, Daniel S Lee3, Shaddy Saba3.
Abstract
The COVID-19 pandemic may have a compounding effect on the substance use of American veterans with posttraumatic stress disorder (PTSD). This study investigated the relationship between PTSD and current reactions to COVID-19 on alcohol and cannabis use among veterans who completed a survey 1 month prior to the pandemic in the USA and a 6-month follow-up survey. We hypothesized that veterans with PTSD would experience more negative reactions to COVID-19 and increased alcohol and cannabis use behaviors over those without PTSD. Veterans with PTSD prior to the pandemic, relative to those without, endorsed poorer reactions, greater frequency of alcohol use, and greater cannabis initiation and use during the pandemic. Veterans with PTSD may use substances to manage COVID-related stress. Clinicians may see an increase in substance use among this group during and after the pandemic and may need to implement specific behavioral interventions to mitigate the negative effects of COVID-19.Entities:
Keywords: Alcohol; COVID-19; Cannabis; Posttraumatic stress disorder; Veterans
Year: 2021 PMID: 34466132 PMCID: PMC8390086 DOI: 10.1007/s11469-021-00620-0
Source DB: PubMed Journal: Int J Ment Health Addict ISSN: 1557-1874 Impact factor: 11.555
Fig. 1Flow of participant recruitment
Sample description
| All participants ( | |
|---|---|
| M (SD) or N (%) | |
| Age | 34.6 (3.51) |
| Race/ethnicity | |
| Hispanic/Latinx | 90 (8.8%) |
| Black/African American | 62 (6.0%) |
| Asian | 12 (1.2%) |
| White | 850 (82.9%) |
| Multiracial/other | 11 (1.1%) |
| Gender | |
| Men | 917 (89.5%) |
| Women | 96 (9.3%) |
| Other | 12 (1.2%) |
| Branch | |
| Air Force | 123 (12.0%) |
| Army | 722 (70.4%) |
| Marine Corps | 94 (9.2%) |
| Navy | 86 (8.4%) |
| Combat exposure | |
| Any combat exposure | 985 (96.1%) |
| Combat severity | 5.05 (2.13) |
| PTSD | |
| PCL-5 positive screen | 320 (31.2%) |
| PCL-5 severity score | 21.60 (15.35) |
Note: PTSD posttraumatic stress disorder, PCL-5 posttraumatic stress disorder checklist for DSM-5
Means and standard deviations of individual reactions to COVID items for the first 3 and past 3 months of the pandemic
| First 3 months of the pandemic (March, April, May 2020) | Past 3 months of the pandemic (June, July, August 2020) | Standardized difference (Cohen’s | |
|---|---|---|---|
| Feel nervous, anxious, or on edge | 1.08 (0.84) | 1.42 (1.09) | 0.35 [0.26, 0.43] |
| Feel depressed | 1.05 (0.88) | 1.36 (1.11) | 0.30 [0.22, 0.39] |
| Feel lonely | 1.07 (0.87) | 1.34 (1.14) | 0.26 [0.18, 0.34] |
| Sleep less than typical | 1.02 (0.85) | 1.37 (1.12) | 0.34 [0.26, 0.43] |
| Have physical reactions, such as sweating, trouble breathing, nausea, or a pounding heart | 1.00 (0.85) | 1.27 (1.12) | 0.26 [0.19, 0.35] |
| Was stressed by the restrictions on leaving home | 1.14 (0.91) | 1.47 (1.17) | 0.31 [0.23, 0.39] |
| Feel that your family relationships were suffering | 1.06 (0.87) | 1.31 (1.11) | 0.25 [0.17, 0.33] |
| Feel that your social relationships were suffering | 1.10 (0.88) | 1.34 (1.14) | 0.23 [0.15, 0.32] |
| Was stressed about finances | 1.15 (0.95) | 1.49 (1.20) | 0.18 [0.10, 0.26] |
| 1.07 (0.45) | 1.37 (0.63) | 0.55 [0.47, 0.62] |
Note: Higher mean reflects “poorer” COVID-related reactions. Means reflect response options of 1 (a little bit) and 2 (a moderate amount) on a scale from 0 to 4
Changes in substance use outcomes from Time 1 to Time 2
| Substance use | ||||
|---|---|---|---|---|
| Alcohol use days (past 30 days) | 11.37 (5.21) | 8.82 (6.05) | 12.32 (1024) | < 0.001 |
| Binge drinking days (past 30 days) | 5.09 (3.61) | 3.39 (3.14) | 15.27 (1024) | < 0.001 |
| Average drinks per occasion (past 30 days)a | 5.59 (2.56) | 4.32 (2.20) | 14.23 (977) | < 0.001 |
| Max drinks on one occasion (past 30 days)a | 7.77 (2.84) | 5.88 (2.11) | 20.54 (977) | < 0.001 |
| Any cannabis use (lifetime) | 200 (19.5%) | 314 (30.7%) | 220.59 (1, 1024) | < 0.001 |
| Cannabis use days among full sample (past 30 days) | 1.12 (3.74) | 1.23 (3.81) | 0.99 (1024) | 0.323 |
| Cannabis use days among lifetime users (past 30 days)b | 3.67 (6.04) | 4.02 (6.01) | 0.98 (313) | 0.322 |
Note: aAmong past 30-day drinkers only. bAmong lifetime cannabis users only
Fig. 2Past 30-day alcohol outcomes at time 2 by Time 1 PTSD status. Note. Figure contains estimated marginal means and 95% confidence intervals. PTSD posttraumatic stress disorder. Models controlled for age, race/ethnicity, gender, combat severity, and the Time 1 outcome
Fig. 3Cannabis outcome at Time 2 for lifetime cannabis users by time 1 PTSD status. Note. Figure contains estimated marginal means and 95% confidence intervals. PTSD posttraumatic stress disorder. Models controlled for age, race/ethnicity, gender, combat severity, and the Time 1 outcome. Cannabis use days are days in the past 30 days
Fig. 4Interaction plot for PTSD and poor reactions to COVID during the first 3 months of the pandemic for alcohol use days outcomes
Fig. 5Interaction plot for PTSD and poor reactions to COVID during the first 3 months of the pandemic for average drinks per occasion outcome