| Literature DB >> 34463862 |
Tyler J VanderWeele1,2,3, Eric S Kim4,5,1,6, Julia S Nakamura7, Scott W Delaney5,6, Ed Diener8.
Abstract
PURPOSE: Growing evidence documents strong associations between overall life satisfaction and favorable health and well-being outcomes. However, because most previous studies have assessed satisfaction with one's life as a whole, we know little about whether specific domains of life satisfaction (e.g., satisfaction with family life, income) might be responsible for longitudinally driving better health and well-being.Entities:
Keywords: Domains of life satisfaction; Older adults; Outcome-wide epidemiology; Public health
Mesh:
Year: 2021 PMID: 34463862 PMCID: PMC8406389 DOI: 10.1007/s11136-021-02977-0
Source DB: PubMed Journal: Qual Life Res ISSN: 0962-9343 Impact factor: 3.440
Characteristics of participants at pre-baseline by categories of satisfaction with overall life (N = 10,442)
| Participant characteristics | Overall life satisfaction | |||||
|---|---|---|---|---|---|---|
| Tertile 1 ( | Tertile 2 ( | Tertile 3 ( | ||||
| No. (%) | Mean (SD) | No. (%) | Mean (SD) | No. (%) | Mean (SD) | |
| Age (year; range: 48–96) | 63.7 (9.1) | 66.5 (9.6) | 67.5 (9.4) | |||
| Female (%) | 524 (64.8) | 1890 (62.1) | 3869 (58.7) | |||
| Race/ethnicity (%) | ||||||
| White | 518 (64.0) | 2117 (69.5) | 5241 (79.6) | |||
| Black | 154 (19.0) | 525 (17.2) | 710 (10.8) | |||
| Hispanic | 116 (14.3) | 316 (10.4) | 485 (7.4) | |||
| Other | 21 (2.6) | 87 (2.9) | 149 (2.3) | |||
| Married (%) | 366 (45.2) | 1760 (57.8) | 4573 (69.4) | |||
| Annual household income (%) | ||||||
| < $50,000 | 619 (76.5) | 1926 (63.2) | 3299 (50.1) | |||
| $50,000–$74,999 | 97 (12.0) | 466 (15.3) | 1136 (17.3) | |||
| $75,000–$99,999 | 52 (6.4) | 261 (8.6) | 713 (10.8) | |||
| ≥ $100,000 | 41 (5.1) | 393 (12.9) | 1439 (21.9) | |||
| Total wealth (%) | ||||||
| 1st quintile | 353 (43.6) | 747 (24.5) | 827 (12.6) | |||
| 2nd quintile | 184 (22.7) | 740 (24.3) | 1111 (16.9) | |||
| 3rd quintile | 132 (16.3) | 619 (20.3) | 1364 (20.7) | |||
| 4th quintile | 89 (11.0) | 546 (17.9) | 1530 (23.2) | |||
| 5th quintile | 51 (6.3) | 394 (12.9) | 1755 (26.6) | |||
| Education (%) | ||||||
| < High school | 195 (24.2) | 555 (18.3) | 851 (13.0) | |||
| High school | 462 (57.3) | 1777 (58.5) | 3542 (53.9) | |||
| ≥ College | 150 (18.6) | 707 (23.3) | 2175 (33.1) | |||
| Employed (%) | 301 (37.2) | 1272 (41.8) | 2844 (43.2) | |||
| Health insurance (%) | 683 (84.5) | 2794 (91.8) | 6299 (95.7) | |||
| Geographic region (%) | ||||||
| Northeast | 143 (17.7) | 437 (14.4) | 935 (14.2) | |||
| Midwest | 186 (23.1) | 790 (26.0) | 1775 (27.0) | |||
| South | 318 (39.4) | 1218 (40.1) | 2572 (39.1) | |||
| West | 160 (19.8) | 596 (19.6) | 1300 (19.8) | |||
| Childhood abuse (%) | 143 (17.8) | 265 (8.8) | 389 (6.0) | |||
| Diabetes (%) | 230 (28.5) | 729 (24.0) | 1068 (16.2) | |||
| Hypertension (%) | 517 (64.2) | 1802 (59.2) | 3514 (53.4) | |||
| Stroke (%) | 86 (10.6) | 197 (6.5) | 337 (5.1) | |||
| Cancer (%) | 100 (12.4) | 427 (14.1) | 904 (13.7) | |||
| Heart disease (%) | 252 (31.2) | 712 (23.4) | 1217 (18.5) | |||
| Lung disease (%) | 139 (17.2) | 308 (10.1) | 387 (5.9) | |||
| Arthritis (%) | 533 (65.9) | 1923 (63.3) | 3600 (54.7) | |||
| Overweight/obesity (%) | 623 (78.6) | 2266 (75.2) | 4630 (71.0) | |||
| Physical function limitations (%) | 409 (50.6) | 864 (28.4) | 778 (11.8) | |||
| Cognitive impairment (%) | 160 (20.0) | 509 (16.9) | 812 (12.5) | |||
| Chronic pain (%) | 510 (63.1) | 1357 (44.6) | 1779 (27.0) | |||
| Self-rated health (range: 1–5) | 2.3 (1.0) | 2.9 (1.0) | 3.6 (0.9) | |||
| Heavy drinking (%) | 50 (7.8) | 189 (7.8) | 434 (8.0) | |||
| Smoking (%) | 191 (23.7) | 473 (15.7) | 636 (9.7) | |||
| Frequent physical activity (%) | 454 (56.3) | 2054 (67.5) | 5237 (79.6) | |||
| Sleep problems (%) | 318 (64.4) | 811 (45.7) | 1223 (34.4) | |||
| Never | 305 (37.7) | 836 (27.5) | 1436 (21.8) | |||
| < 1x/week | 265 (32.8) | 1023 (33.6) | 2065 (31.4) | |||
| ≥ 1x/week | 239 (29.5) | 1184 (38.9) | 3082 (46.8) | |||
| Positive affect (range: 1–5) | 2.7 (0.7) | 3.2 (0.7) | 3.9 (0.7) | |||
| Life satisfaction (range: 1–7) | 2.8 (1.4) | 4.2 (1.3) | 5.6 (1.2) | |||
| Optimism (range: 1–6) | 3.5 (1.0) | 4.2 (0.9) | 4.8 (0.9) | |||
| Purpose in life (range: 1–6) | 3.8 (1.0) | 4.4 (0.9) | 5.0 (0.8) | |||
| Mastery (range: 1–6) | 3.9 (1.2) | 4.5 (1.0) | 5.1 (1.0) | |||
| Health mastery (range: 1–10) | 5.3 (2.9) | 6.7 (2.3) | 8.0 (1.9) | |||
| Financial mastery (range: 1–10) | 4.7 (3.3) | 6.5 (2.6) | 7.9 (2.1) | |||
| Depression (%) | 427 (52.8) | 582 (19.1) | 335 (5.1) | |||
| Depressive symptoms (range: 0–8) | 3.9 (2.6) | 1.8 (2.0) | 0.7 (1.2) | |||
| Hopelessness (range: 1–6) | 3.7 (1.3) | 2.7 (1.2) | 1.9 (1.0) | |||
| Negative affect (range: 1–5) | 2.6 (0.8) | 1.9 (0.6) | 1.5 (0.5) | |||
| Perceived constraints (range: 1–6) | 3.4 (1.3) | 2.5 (1.1) | 1.8 (1.0) | |||
| Loneliness (range: 1–3) | 2.1 (0.6) | 1.6 (0.5) | 1.3 (0.4) | |||
| Not living with spouse/partner (%) | 388 (51.0) | 1123 (38.5) | 1713 (26.9) | |||
| Contact children < 1x/week (%) | 259 (33.1) | 847 (28.6) | 1499 (23.2) | |||
| Contact other family < 1x/week (%) | 393 (49.2) | 1381 (46.1) | 2900 (44.6) | |||
| Contact friends < 1x/week (%) | 368 (45.9) | 1092 (36.4) | 2015 (30.9) | |||
| Openness (range: 1–4) | 2.7 (0.6) | 2.8 (0.5) | 3.0 (0.5) | |||
| Conscientiousness (range: 1–4) | 3.2 (0.5) | 3.3 (0.5) | 3.5 (0.4) | |||
| Extraversion (range: 1–4) | 2.8 (0.6) | 3.0 (0.5) | 3.3 (0.5) | |||
| Agreeableness (range: 1–4) | 3.4 (0.5) | 3.4 (0.5) | 3.6 (0.4) | |||
| Neuroticism (range: 1–4) | 2.6 (0.7) | 2.2 (0.6) | 1.9 (0.5) | |||
This table was created based on non-imputed data
All variables in Table 1 were used as covariates, and assessed in the pre-baseline wave (t0; 2008/2010)
The percentages in some sections may not add up to 100% due to rounding
Satisfaction with individual domains of life and subsequent health and well-being (Health and Retirement Study [HRS]: N = 13,752)
| Domain of Life Satisfaction | ||||||||
|---|---|---|---|---|---|---|---|---|
| Tertile 1 (reference) | Tertile 3 | Tertile 3 | Tertile 3 | Tertile 3 | Tertile 3 | Tertile 3 | Tertile 3 | |
| All-cause mortality | 1.00 | 0.97 (0.82, 1.14) | 1.05 (0.89, 1.23) | 0.87 (0.75, 1.02) | 1.05 (0.89, 1.23) | 1.01 (0.85, 1.21) | 0.95 (0.80, 1.13) | 0.79 (0.66, 0.95)* |
| Number of chronic conditions | 0.00 | − 0.02 (− 0.06, 0.01) | 0.00 (− 0.04, 0.03) | − 0.02 (− 0.05, 0.02) | − 0.01 (− 0.04, 0.03) | − 0.06 (− 0.11, 0.00)* | − 0.05 (− 0.11, 0.00) | − 0.05 (− 0.08, − 0.02)** |
| Diabetes | 1.00 | 0.99 (0.90, 1.09) | 1.01 (0.92, 1.12) | 0.99 (0.89, 1.11) | 0.97 (0.88, 1.07) | 0.92 (0.83, 1.02) | 0.95 (0.85, 1.06) | 0.93 (0.84, 1.04) |
| Hypertension | 1.00 | 0.98 (0.92, 1.04) | 0.99 (0.92, 1.05) | 1.00 (0.94, 1.06) | 0.99 (0.93, 1.06) | 0.97 (0.91, 1.04) | 0.98 (0.91, 1.05) | 0.99 (0.92, 1.07) |
| Stroke | 1.00 | 0.94 (0.79, 1.10) | 1.03 (0.87, 1.22) | 0.98 (0.83, 1.17) | 1.02 (0.87, 1.21) | 0.92 (0.73, 1.15) | 0.84 (0.71, 1.00)* | 1.00 (0.82, 1.22) |
| Cancer | 1.00 | 1.04 (0.90, 1.19) | 0.94 (0.84, 1.06) | 0.96 (0.85, 1.08) | 0.99 (0.88, 1.12) | 0.98 (0.85, 1.12) | 0.97 (0.83, 1.12) | 0.96 (0.83, 1.11) |
| Heart disease | 1.00 | 0.98 (0.88, 1.08) | 1.02 (0.92, 1.12) | 1.00 (0.91, 1.10) | 0.98 (0.90, 1.08) | 0.93 (0.83, 1.05) | 0.92 (0.82, 1.03) | 0.91 (0.82, 1.02) |
| Lung disease | 1.00 | 1.05 (0.91, 1.22) | 1.13 (0.98, 1.31) | 1.05 (0.91, 1.21) | 1.05 (0.91, 1.21) | 0.99 (0.85, 1.15) | 1.01 (0.87, 1.18) | 0.98 (0.83, 1.16) |
| Arthritis | 1.00 | 0.97 (0.91, 1.04) | 0.99 (0.93, 1.05) | 0.98 (0.92, 1.04) | 0.98 (0.92, 1.04) | 0.98 (0.92, 1.05) | 0.99 (0.92, 1.06) | 0.98 (0.91, 1.06) |
| Overweight/obesity | 1.00 | 0.98 (0.92, 1.05) | 0.98 (0.92, 1.04) | 0.99 (0.93, 1.06) | 1.02 (0.95, 1.08) | 0.98 (0.91, 1.05) | 1.00 (0.94, 1.07) | 1.01 (0.94, 1.09) |
| Physical functioning limitations | 1.00 | 0.93 (0.84, 1.03) | 0.95 (0.86, 1.06) | 0.86 (0.76, 0.98)* | 0.91 (0.82, 1.00) | 0.79 (0.70, 0.90)*** | 0.80 (0.69, 0.92)** | 0.82 (0.72, 0.94)** |
| Cognitive impairment | 1.00 | 1.07 (0.96, 1.20) | 1.03 (0.91, 1.16) | 0.99 (0.87, 1.12) | 1.06 (0.95, 1.17) | 0.94 (0.83, 1.06) | 0.95 (0.85, 1.06) | 1.05 (0.91, 1.23) |
| Chronic pain | 1.00 | 0.92 (0.85, 1.00)* | 0.94 (0.86, 1.03) | 0.86 (0.79, 0.94)*** | 0.91 (0.84, 0.99)* | 0.87 (0.78, 0.96)** | 0.86 (0.78, 0.96)** | 0.87 (0.79, 0.96)** |
| Self-rated health | 0.00 | 0.14 (0.09, 0.18)*** | 0.12 (0.08, 0.17)*** | 0.21 (0.17, 0.25)*** | 0.13 (0.09, 0.17)*** | 0.19 (0.14, 0.25)*** | 0.19 (0.12, 0.26)*** | 0.32 (0.25, 0.39)*** |
| Heavy drinking | 1.00 | 1.40 (0.95, 2.07) | 1.29 (0.92, 1.81) | 1.15 (0.87, 1.51) | 1.16 (0.89, 1.52) | 1.49 (1.01, 2.21)* | 1.41 (0.83, 2.39) | 0.93 (0.67, 1.30) |
| Smoking | 1.00 | 0.96 (0.82, 1.13) | 1.06 (0.89, 1.27) | 0.95 (0.80, 1.12) | 0.93 (0.79, 1.11) | 0.90 (0.72, 1.12) | 0.97 (0.79, 1.20) | 1.05 (0.85, 1.30) |
| Frequent physical activity | 1.00 | 1.00 (0.94, 1.07) | 1.01 (0.94, 1.08) | 1.03 (0.96, 1.10) | 0.98 (0.91, 1.05) | 1.01 (0.93, 1.09) | 1.01 (0.93, 1.09) | 1.07 (0.98, 1.17) |
| Sleep problems | 1.00 | 1.05 (0.95, 1.15) | 0.98 (0.90, 1.07) | 0.91 (0.81, 1.03) | 0.93 (0.85, 1.03) | 0.89 (0.80, 0.98)* | 0.89 (0.79, 1.01) | 0.96 (0.86, 1.06) |
| Positive affect | 0.00 | 0.20 (0.15, 0.24)*** | 0.20 (0.14, 0.25)*** | 0.37 (0.30, 0.43)*** | 0.33 (0.26, 0.40)*** | 0.29 (0.20, 0.38)*** | 0.24 (0.17, 0.31)*** | 0.04 (− 0.01, 0.10) |
| Life satisfaction | 0.00 | 0.35 (0.28, 0.42)*** | 0.30 (0.19, 0.40)*** | 0.49 (0.44, 0.55)*** | 0.51 (0.46, 0.56)*** | 0.54 (0.45, 0.62)*** | 0.50 (0.42, 0.58)*** | 0.34 (0.28, 0.41)*** |
| Optimism | 0.00 | 0.08 (0.03, 0.13)** | 0.08 (0.02, 0.14)* | 0.16 (0.12, 0.20)*** | 0.18 (0.13, 0.23)*** | 0.18 (0.11, 0.25)*** | 0.17 (0.11, 0.23)*** | − 0.05 (− 0.13, 0.02) |
| Purpose in life | 0.00 | 0.09 (0.03, 0.16)* | 0.10 (0.03, 0.17)** | 0.26 (0.21, 0.31)*** | 0.22 (0.15, 0.28)*** | 0.20 (0.14, 0.27)*** | 0.18 (0.12, 0.24)*** | − 0.01 (− 0.06, 0.04) |
| Mastery | 0.00 | 0.15 (0.09, 0.22)*** | 0.15 (0.10, 0.20)*** | 0.28 (0.22, 0.34)*** | 0.21 (0.16, 0.26)*** | 0.24 (0.17, 0.30)*** | 0.22 (0.15, 0.29)*** | 0.12 (0.06, 0.19)*** |
| Health mastery | 0.00 | 0.14 (0.08, 0.20)*** | 0.14 (0.09, 0.18)*** | 0.19 (0.10, 0.28)*** | 0.10 (0.04, 0.17)** | 0.18 (0.12, 0.25)*** | 0.23 (0.16, 0.31)*** | 0.25 (0.17, 0.32)*** |
| Financial mastery | 0.00 | 0.19 (0.09, 0.29)** | 0.19 (0.11, 0.27)*** | 0.26 (0.20, 0.33)*** | 0.19 (0.11, 0.27)*** | 0.48 (0.37, 0.58)*** | 0.45 (0.38, 0.53)*** | 0.11 (0.04, 0.18)** |
| Depression | 1.00 | 0.73 (0.63, 0.85)*** | 0.76 (0.65, 0.89)*** | 0.54 (0.44, 0.66)*** | 0.56 (0.48, 0.66)*** | 0.61 (0.51, 0.72)*** | 0.62 (0.53, 0.73)*** | 0.78 (0.65, 0.93)** |
| Depressive symptoms | 0.00 | − 0.15 (− 0.19, − 0.11)*** | − 0.13 (− 0.19, − 0.08)*** | − 0.27 (− 0.33, − 0.21)*** | − 0.27 (− 0.34, − 0.20)*** | − 0.26 (− 0.31, − 0.20)*** | − 0.23 (− 0.28, − 0.19)*** | − 0.06 (− 0.11, − 0.01)* |
| Hopelessness | 0.00 | − 0.14 (− 0.19, − 0.09)*** | − 0.14 (− 0.19, − 0.08)*** | − 0.21 (− 0.26, − 0.16)*** | − 0.23 (− 0.28, − 0.18)*** | − 0.29 (− 0.35, − 0.23)*** | − 0.25 (− 0.30, − 0.19)*** | − 0.02 (− 0.07, 0.04) |
| Negative affect | 0.00 | − 0.19 (− 0.25, − 0.13)*** | − 0.18 (− 0.23, − 0.13)*** | − 0.33 (− 0.38, − 0.28)*** | − 0.32 (− 0.40, − 0.24)*** | − 0.32 (− 0.44, − 0.21)*** | − 0.29 (− 0.37, − 0.22)*** | − 0.05 (− 0.10, 0.00) |
| Perceived constraints | 0.00 | − 0.15 (− 0.26, − 0.05)* | − 0.11 (− 0.19, − 0.03)* | − 0.24 (− 0.30, − 0.19)*** | − 0.20 (− 0.26, − 0.15)*** | − 0.27 (− 0.38, − 0.16)*** | − 0.21 (− 0.27, − 0.14)*** | − 0.01 (− 0.08, 0.06) |
| Loneliness | 0.00 | − 0.16 (− 0.24, − 0.08)*** | − 0.19 (− 0.26, − 0.11)*** | − 0.35 (− 0.40, − 0.30)*** | − 0.42 (− 0.47, − 0.37)*** | − 0.31 (− 0.37, − 0.24)*** | − 0.26 (− 0.33, − 0.19)*** | 0.01 (− 0.04, 0.07) |
| Not living with a spouse/partner | 1.00 | 0.92 (0.85, 1.00)* | 0.96 (0.88, 1.04) | 0.85 (0.78, 0.92)*** | 0.82 (0.76, 0.89)*** | 0.92 (0.84, 1.01) | 0.92 (0.84, 1.01) | 0.99 (0.89, 1.09) |
| Contact children < 1x/week | 1.00 | 1.02 (0.87, 1.21) | 1.02 (0.86, 1.21) | 0.96 (0.83, 1.12) | 0.85 (0.74, 0.97)* | 1.00 (0.84, 1.18) | 1.03 (0.88, 1.20) | 1.00 (0.88, 1.13) |
| Contact other family < 1x/week | 1.00 | 1.01 (0.91, 1.12) | 1.06 (0.96, 1.17) | 1.03 (0.95, 1.12) | 0.94 (0.86, 1.02) | 1.02 (0.94, 1.11) | 1.02 (0.94, 1.11) | 0.97 (0.88, 1.08) |
| Contact friends < 1x/week | 1.00 | 1.03 (0.94, 1.12) | 0.96 (0.88, 1.05) | 0.96 (0.87, 1.06) | 1.08 (0.97, 1.21) | 0.98 (0.88, 1.09) | 0.96 (0.87, 1.05) | 1.03 (0.92, 1.16) |
CI confidence interval, OR odds ratio, RR risk ratio
If the reference value is “1,” the effect estimate is OR or RR; if the reference value is “0,” the effect estimate is β
The analytic sample was restricted to those who had participated in the baseline wave (t1; 2012 or 2014). Multiple imputation was performed to impute missing data on the exposure, covariates, and outcomes. For the first six domains of life satisfaction (home, city/town, daily life/leisure activities, family, financial situation, and income), all models controlled for pre-baseline sociodemographic characteristics, outcome variables, and the exposure. For the last domain of life satisfaction (satisfaction with health), all models controlled for baseline sociodemographic characteristics and outcome variables
*p < 0.05 before Bonferroni correction; **p < 0.01 before Bonferroni correction; ***p < 0.05 after Bonferroni correction (the p value cutoff for Bonferroni correction is p = 0.05/35 outcomes = p < 0.001)
Robustness to unmeasured confounding (E values) for the associations between satisfaction with individual domains of life (3rd tertile vs. 1st tertile) and subsequent health and well-being (N = 13,752)
| Domain of life satisfaction | |||||||
|---|---|---|---|---|---|---|---|
| Tertile 3 | Tertile 3 | Tertile 3 | Tertile 3 | Tertile 3 | Tertile 3 | Tertile 3 | |
| All-cause mortality | 1.23 (1.00) | 1.26 (1.00) | 1.56 (1.00) | 1.27 (1.00) | 1.12 (1.00) | 1.29 (1.00) | 1.84 (1.30) |
| Number of chronic conditions | 1.17 (1.00) | 1.06 (1.00) | 1.13 (1.00) | 1.09 (1.00) | 1.29 (1.08) | 1.27 (1.05) | 1.26 (1.15) |
| Diabetes | 1.11 (1.00) | 1.12 (1.00) | 1.09 (1.00) | 1.20 (1.00) | 1.39 (1.00) | 1.29 (1.00) | 1.35 (1.00) |
| Hypertension | 1.17 (1.00) | 1.14 (1.00) | 1.06 (1.00) | 1.12 (1.00) | 1.20 (1.00) | 1.18 (1.00) | 1.09 (1.00) |
| Stroke | 1.34 (1.00) | 1.21 (1.00) | 1.14 (1.00) | 1.18 (1.00) | 1.39 (1.00) | 1.66 (1.04) | 1.06 (1.00) |
| Cancer | 1.23 (1.00) | 1.31 (1.00) | 1.26 (1.00) | 1.10 (1.00) | 1.17 (1.00) | 1.23 (1.00) | 1.25 (1.00) |
| Heart disease | 1.19 (1.00) | 1.15 (1.00) | 1.03 (1.00) | 1.14 (1.00) | 1.35 (1.00) | 1.39 (1.00) | 1.42 (1.00) |
| Lung disease | 1.29 (1.00) | 1.52 (1.00) | 1.27 (1.00) | 1.27 (1.00) | 1.10 (1.00) | 1.12 (1.00) | 1.15 (1.00) |
| Arthritis | 1.20 (1.00) | 1.12 (1.00) | 1.18 (1.00) | 1.17 (1.00) | 1.15 (1.00) | 1.12 (1.00) | 1.14 (1.00) |
| Overweight/obesity | 1.14 (1.00) | 1.17 (1.00) | 1.10 (1.00) | 1.15 (1.00) | 1.16 (1.00) | 1.04 (1.00) | 1.10 (1.00) |
| Physical functioning limitations | 1.37 (1.00) | 1.27 (1.00) | 1.59 (1.18) | 1.44 (1.00) | 1.83 (1.46) | 1.82 (1.40) | 1.73 (1.34) |
| Cognitive impairment | 1.35 (1.00) | 1.19 (1.00) | 1.13 (1.00) | 1.30 (1.00) | 1.33 (1.00) | 1.29 (1.00) | 1.29 (1.00) |
| Chronic pain | 1.39 (1.04) | 1.32 (1.00) | 1.59 (1.33) | 1.42 (1.08) | 1.58 (1.26) | 1.59 (1.26) | 1.57 (1.26) |
| Self-rated health | 1.52 (1.40) | 1.49 (1.35) | 1.72 (1.61) | 1.50 (1.38) | 1.67 (1.53) | 1.67 (1.50) | 2.01 (1.83) |
| Heavy drinking | 2.16 (1.00) | 1.90 (1.00) | 1.57 (1.00) | 1.59 (1.00) | 2.35 (1.10) | 2.17 (1.00) | 1.35 (1.00) |
| Smoking | 1.25 (1.00) | 1.31 (1.00) | 1.29 (1.00) | 1.35 (1.00) | 1.48 (1.00) | 1.19 (1.00) | 1.29 (1.00) |
| Frequent physical activity | 1.07 (1.00) | 1.08 (1.00) | 1.21 (1.00) | 1.19 (1.00) | 1.10 (1.00) | 1.08 (1.00) | 1.34 (1.00) |
| Sleep problems | 1.26 (1.00) | 1.14 (1.00) | 1.42 (1.00) | 1.34 (1.00) | 1.50 (1.15) | 1.49 (1.00) | 1.27 (1.00) |
| Positive affect | 1.68 (1.57) | 1.68 (1.54) | 2.14 (1.97) | 2.04 (1.87) | 1.93 (1.73) | 1.80 (1.64) | 1.24 (1.00) |
| Life satisfaction | 2.09 (1.91) | 1.95 (1.71) | 2.51 (2.36) | 2.55 (2.41) | 2.64 (2.41) | 2.53 (2.31) | 2.08 (1.91) |
| Optimism | 1.36 (1.21) | 1.37 (1.18) | 1.58 (1.46) | 1.63 (1.51) | 1.64 (1.47) | 1.61 (1.46) | 1.00 (1.00) |
| Purpose in life | 1.39 (1.20) | 1.42 (1.24) | 1.85 (1.73) | 1.74 (1.58) | 1.70 (1.54) | 1.64 (1.49) | 1.00 (1.00) |
| Mastery | 1.57 (1.40) | 1.56 (1.42) | 1.90 (1.75) | 1.72 (1.59) | 1.78 (1.61) | 1.74 (1.56) | 1.48 (1.30) |
| Health mastery | 1.53 (1.37) | 1.52 (1.39) | 1.66 (1.46) | 1.43 (1.26) | 1.64 (1.47) | 1.78 (1.59) | 1.81 (1.63) |
| Financial mastery | 1.67 (1.44) | 1.66 (1.46) | 1.86 (1.70) | 1.66 (1.47) | 2.45 (2.19) | 2.39 (2.19) | 1.46 (1.26) |
| Depression | 2.08 (1.64) | 1.96 (1.50) | 3.10 (2.39) | 2.95 (2.38) | 2.67 (2.11) | 2.61 (2.09) | 1.89 (1.36) |
| Depressive symptoms | 1.56 (1.44) | 1.51 (1.37) | 1.87 (1.73) | 1.88 (1.71) | 1.84 (1.70) | 1.78 (1.65) | 1.30 (1.10) |
| Hopelessness | 1.52 (1.39) | 1.53 (1.38) | 1.71 (1.59) | 1.76 (1.64) | 1.93 (1.77) | 1.82 (1.67) | 1.14 (1.00) |
| Negative affect | 1.67 (1.52) | 1.63 (1.50) | 2.04 (1.90) | 2.02 (1.83) | 2.02 (1.77) | 1.94 (1.76) | 1.27 (1.01) |
| Perceived constraints | 1.57 (1.32) | 1.45 (1.22) | 1.80 (1.66) | 1.69 (1.55) | 1.88 (1.63) | 1.71 (1.55) | 1.09 (1.00) |
| Loneliness | 1.58 (1.39) | 1.65 (1.48) | 2.09 (1.95) | 2.30 (2.16) | 1.97 (1.81) | 1.84 (1.68) | 1.00 (1.00) |
| Not living with a spouse/partner | 1.39 (1.07) | 1.26 (1.00) | 1.63 (1.39) | 1.73 (1.50) | 1.40 (1.00) | 1.40 (1.00) | 1.13 (1.00) |
| Contact children < 1x/week | 1.18 (1.00) | 1.15 (1.00) | 1.24 (1.00) | 1.63 (1.19) | 1.06 (1.00) | 1.20 (1.00) | 1.02 (1.00) |
| Contact other family < 1x/week | 1.12 (1.00) | 1.31 (1.00) | 1.20 (1.00) | 1.34 (1.00) | 1.16 (1.00) | 1.17 (1.00) | 1.20 (1.00) |
| Contact friends < 1x/week | 1.19 (1.00) | 1.24 (1.00) | 1.25 (1.00) | 1.39 (1.00) | 1.16 (1.00) | 1.25 (1.00) | 1.22 (1.00) |
See VanderWeele and Ding [32] for the formula for calculating E values
The E values for effect estimates are the minimum strength of association on the risk ratio scale that an unmeasured confounder would need to have with both the exposure and the outcome to fully explain away the observed association between the exposure and outcome, conditional on the measured covariates
The E values for the limit of the 95% confidence interval (CI) closest to the null denote the minimum strength of association on the risk ratio scale that an unmeasured confounder would need to have with both the exposure and the outcome to shift the confidence interval to include the null value, conditional on the measured covariates