Steven J Drews1,2, Paul Van Caeseele3, Jared Bullard3, L Robbin Lindsay4, Teresa Gaziano5, Michelle P Zeller6,7, Debra Lane8, Momar Ndao9, Vanessa G Allen10,11, Andrea K Boggild12,13, Sheila F O'Brien14, Daniel Marko15,16, Charles Musuka15,16, Muhamad Almiski15,16, Mark Bigham17. 1. Microbiology, Donation Policy and Studies, Canadian Blood Services, Edmonton, Alberta, Canada. 2. Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada. 3. Cadham Provincial Laboratory, Winnipeg, Manitoba, Canada. 4. Zoonotic Diseases and Special Pathogens Section, National Microbiology Laboratory, Winnipeg, Manitoba, Canada. 5. Medical Laboratory and Stem Cell Services, Canadian Blood Services, Brampton, Ontario, Canada. 6. Medical Laboratory and Stem Cell Services, Canadian Blood Services, Ancaster, Ontario, Canada. 7. McMaster Centre for Transfusion Research, McMaster University, Hamilton, Ontario, Canada. 8. Medical Laboratory and Stem Cell Services, Canadian Blood Services, Winnipeg, Manitoba, Canada. 9. National Reference Centre for Parasitology, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada. 10. Public Health Ontario, Toronto, Ontario, Canada. 11. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. 12. Tropical Disease Unit, Division of Infectious Diseases, University Health Network, Toronto, Ontario, Canada. 13. Department of Medicine, University of Toronto, Toronto, Ontario, Canada. 14. Epidemiology and Surveillance, Donation Policy and Studies, Canadian Blood Services, Ottawa, Ontario, Canada. 15. Department of Pathology, University of Manitoba, Winnipeg, Manitoba, Canada. 16. Shared Health, Winnipeg, Manitoba, Canada. 17. Medical Laboratory and Stem Cell Services, Canadian Blood Services, Vancouver, British Columbia, Canada.
Abstract
BACKGROUND AND OBJECTIVES: We describe the third documented case of autochthonous human babesiosis in Canada and the second in a Canadian blood donor. MATERIALS AND METHODS: Multiple laboratory investigations were carried out on the donor and the immunocompromised recipient of an associated, potentially infectious red blood cell product. RESULTS: The donor had not travelled except for outdoor exposure in south-eastern Manitoba, followed by illness and hospital admission. The donor had a notable parasitaemia, positive for Babesia microti using whole blood nucleic acid testing (NAT). The recipient was negative for B. microti by both serology and NAT. CONCLUSION: There was no evidence of transfusion-transmitted babesiosis.
BACKGROUND AND OBJECTIVES: We describe the third documented case of autochthonous human babesiosis in Canada and the second in a Canadian blood donor. MATERIALS AND METHODS: Multiple laboratory investigations were carried out on the donor and the immunocompromised recipient of an associated, potentially infectious red blood cell product. RESULTS: The donor had not travelled except for outdoor exposure in south-eastern Manitoba, followed by illness and hospital admission. The donor had a notable parasitaemia, positive for Babesia microti using whole blood nucleic acid testing (NAT). The recipient was negative for B. microti by both serology and NAT. CONCLUSION: There was no evidence of transfusion-transmitted babesiosis.
Authors: Ziyad O Allehebi; Farhan M Khan; Mark Robbins; Elizabeth Simms; Richard Xiang; Allam Shawwa; L Robbin Lindsay; Antonia Dibernardo; Clarice d'Entremont; Alex Crowell; Jason J LeBlanc; David J Haldane Journal: Emerg Infect Dis Date: 2022-06 Impact factor: 16.126
Authors: Sheila F O'Brien; Steven J Drews; Antoine Lewin; Carla Osiowy; Michael A Drebot; Christian Renaud Journal: Can Commun Dis Rep Date: 2022-04-06