Transplantation of Mesenchymal Cells Including the Blastema in Regenerating Zebrafish Fin.

Regeneration of fish fins and urodele limbs occurs via formation of the blastema, which is a mass of mesenchymal cells formed at the amputated site and is essential for regeneration. The blastema transplantation, a novel technique developed in our previous studies ( Shibata et al., 2016 ; Yoshinari et al., 2012 ) is a useful approach for tracking and manipulating the blastema cells during fish fin regeneration.