Literature DB >> 34455816

GSK2256294 Decreases sEH (Soluble Epoxide Hydrolase) Activity in Plasma, Muscle, and Adipose and Reduces F2-Isoprostanes but Does Not Alter Insulin Sensitivity in Humans.

James M Luther1, Justina Ray2, Dawei Wei1, John R Koethe3, Latoya Hannah3, Anthony DeMatteo1, Robert Manning1, Andrew S Terker4, Dungeng Peng1, Hui Nian5, Chang Yu5, Mona Mashayekhi6, Jorge Gamboa1, Nancy J Brown1,7.   

Abstract

[Figure: see text].

Entities:  

Keywords:  eicosanoids; epoxide hydrolases; hypertension; insulin resistance; oxidative stress

Mesh：

Substances：

Year:  2021        PMID： 34455816      PMCID： PMC8429121          DOI： 10.1161/HYPERTENSIONAHA.121.17659

Source DB:  PubMed          Journal:  Hypertension        ISSN： 0194-911X            Impact factor:   9.897


  36 in total

1.  CYP2J2 and EETs protect against lung ischemia/reperfusion injury via anti-inflammatory effects in vivo and in vitro.

Authors:  Wenshu Chen; Shijiang Yang; Wei Ping; Xiangning Fu; Qinzi Xu; Jianing Wang
Journal:  Cell Physiol Biochem       Date:  2015-03-30

2.  Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis.

Authors:  Pengcheng Luo; Hsin-Hsin Chang; Yiqiang Zhou; Shali Zhang; Sung Hee Hwang; Christophe Morisseau; Cong-Yi Wang; Edward W Inscho; Bruce D Hammock; Mong-Heng Wang
Journal:  J Pharmacol Exp Ther       Date:  2010-05-03       Impact factor: 4.030

Review 3.  Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health.

Authors:  Christophe Morisseau; Bruce D Hammock
Journal:  Annu Rev Pharmacol Toxicol       Date:  2012-09-27       Impact factor: 13.820

4.  Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage.

Authors:  J D Morrow; B Frei; A W Longmire; J M Gaziano; S M Lynch; Y Shyr; W E Strauss; J A Oates; L J Roberts
Journal:  N Engl J Med       Date:  1995-05-04       Impact factor: 91.245

5.  The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt.

Authors:  Jorge H Capdevila; Nataliya Pidkovka; Shaojun Mei; Yan Gong; John R Falck; John D Imig; Raymond C Harris; Wenhui Wang
Journal:  J Biol Chem       Date:  2013-12-24       Impact factor: 5.157

Review 6.  Oxidative stress in chronic vascular disease: From prediction to prevention.

Authors:  Francesca Santilli; Damiano D'Ardes; Giovanni Davì
Journal:  Vascul Pharmacol       Date:  2015-09-10       Impact factor: 5.773

7.  Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors.

Authors:  W B Campbell; D Gebremedhin; P F Pratt; D R Harder
Journal:  Circ Res       Date:  1996-03       Impact factor: 17.367

8.  Salt intake and insulin sensitivity in healthy human volunteers.

Authors:  Raymond R Townsend; Shiv Kapoor; Christopher B McFadden
Journal:  Clin Sci (Lond)       Date:  2007-08       Impact factor: 6.124

9.  Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue.

Authors:  Ahmed Bettaieb; Naoto Nagata; Daniel AbouBechara; Samah Chahed; Christophe Morisseau; Bruce D Hammock; Fawaz G Haj
Journal:  J Biol Chem       Date:  2013-04-10       Impact factor: 5.157

10.  The Epoxyeicosatrienoic Acid Pathway Enhances Hepatic Insulin Signaling and is Repressed in Insulin-Resistant Mouse Liver.

Authors:  Alexander Schäfer; Susanne Neschen; Melanie Kahle; Hakan Sarioglu; Tobias Gaisbauer; Axel Imhof; Jerzy Adamski; Stefanie M Hauck; Marius Ueffing
Journal:  Mol Cell Proteomics       Date:  2015-06-12       Impact factor: 5.911
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  4 in total

1.  The soluble epoxide hydrolase inhibitor GSK2256294 decreases the proportion of adipose pro-inflammatory T cells.

Authors:  Mona Mashayekhi; Celestine N Wanjalla; Christian M Warren; Joshua D Simmons; Kakali Ghoshal; Mark Pilkinton; Samuel S Bailin; Curtis L Gabriel; Ambra Pozzi; John R Koethe; Nancy J Brown; Spyros A Kalams; J Matthew Luther
Journal:  Prostaglandins Other Lipid Mediat       Date:  2021-12-15       Impact factor: 3.072

2.  Designing a Small Fluorescent Inhibitor to Investigate Soluble Epoxide Hydrolase Engagement in Living Cells.

Authors:  Steffen Brunst; Julia Schönfeld; Peter Breunig; Luisa D Burgers; Murphy DeMeglio; Johanna H M Ehrler; Felix F Lillich; Lilia Weizel; Jasmin K Hefendehl; Robert Fürst; Ewgenij Proschak; Kerstin Hiesinger
Journal:  ACS Med Chem Lett       Date:  2022-06-14       Impact factor: 4.632

Review 3.  Soluble Epoxide Hydrolase as a Therapeutic Target for Neuropsychiatric Disorders.

Authors:  Jiajing Shan; Kenji Hashimoto
Journal:  Int J Mol Sci       Date:  2022-04-29       Impact factor: 6.208

Review 4.  Soluble Epoxide Hydrolase and Diabetes Complications.

Authors:  Natasha Z Anita; Walter Swardfager
Journal:  Int J Mol Sci       Date:  2022-06-02       Impact factor: 6.208
  4 in total

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