| Literature DB >> 34453742 |
Omar Al Hussein Alawamlh1, Ryan Flannigan1, Russell Hayden1, Marc Goldstein1, Philip S Li1, Richard K Lee2.
Abstract
Testicular torsion (TT) is a common urologic emergency that can occur at any age. It is most common in newborns and during puberty. Prompt evaluation and management is required to salvage the testis following an episode of torsion. TT brings about damage to testicular tissue and spermatogenesis through various hypothesized mechanisms; however there is a consensus that the effects of ischemia, ischemia-reperfusion injury, and oxidative stress account for the most destructive effects. Numerous studies have examined the effects of various agents and therapies in limiting the effects of TT on the testis.Entities:
Keywords: Fertility; Ischemia; Ischemia-reperfusion; Oxidative stress; Spermatogenesis; Testicular torsion
Mesh:
Year: 2021 PMID: 34453742 DOI: 10.1007/978-3-030-77779-1_14
Source DB: PubMed Journal: Adv Exp Med Biol ISSN: 0065-2598 Impact factor: 2.622