Literature DB >> 3444523

Sex hormones and cognitive functioning in men.

K Christiansen1, R Knussmann.   

Abstract

Blood and saliva samples were obtained from 117 healthy young men, following which radioimmunoassays were used to determine the serum concentrations of testosterone (Tser), 5 alpha-dihydrotestosterone (DHT), and the level of free testosterone (Tsal) in the saliva. The cognitive functioning was determined by five spatial and six verbal ipsative test scores, reflecting intra-individual variance in the performance of these tasks, independent of the person's general level of achievement. Within the normal physiological range of androgen levels--especially Tser and to a lesser extent DHT and Tsal--showed a significantly positive correlation with measures of spatial ability and field dependence-independence and a significantly negative correlation with measures of verbal production.

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Year:  1987        PMID: 3444523     DOI: 10.1159/000118389

Source DB:  PubMed          Journal:  Neuropsychobiology        ISSN: 0302-282X            Impact factor:   2.328


  26 in total

1.  Testosterone increases analgesia, anxiolysis, and cognitive performance of male rats.

Authors:  C A Frye; A M Seliga
Journal:  Cogn Affect Behav Neurosci       Date:  2001-12       Impact factor: 3.282

2.  Sex steroid hormones and cognitive functioning in healthy, older men.

Authors:  Rose H Matousek; Barbara B Sherwin
Journal:  Horm Behav       Date:  2010-01-15       Impact factor: 3.587

Review 3.  Estrogen actions in the brain and the basis for differential action in men and women: a case for sex-specific medicines.

Authors:  Glenda E Gillies; Simon McArthur
Journal:  Pharmacol Rev       Date:  2010-04-14       Impact factor: 25.468

4.  Assessment of the effects of sex and sex hormones on spatial cognition in adult rats using the Barnes maze.

Authors:  M N Locklear; M F Kritzer
Journal:  Horm Behav       Date:  2014-06-14       Impact factor: 3.587

Review 5.  Androgen replacement therapy: present and future.

Authors:  Louis J G Gooren; Mathijs C M Bunck
Journal:  Drugs       Date:  2004       Impact factor: 9.546

Review 6.  Androgen deficiency and aging in men.

Authors:  R S Swerdloff; C Wang
Journal:  West J Med       Date:  1993-11

7.  Testosterone influences spatial strategy preferences among adult male rats.

Authors:  Mark D Spritzer; Elliott C Fox; Gregory D Larsen; Christopher G Batson; Benjamin A Wagner; Jack Maher
Journal:  Horm Behav       Date:  2013-04-15       Impact factor: 3.587

Review 8.  Androgen therapy in the aging male.

Authors:  Bruno Lunenfeld
Journal:  World J Urol       Date:  2003-10-24       Impact factor: 4.226

Review 9.  Spatial cognition in humans: possible modulation by androgens and estrogens.

Authors:  E Hampson
Journal:  J Psychiatry Neurosci       Date:  1995-11       Impact factor: 6.186

10.  In vitro binding assays using (3)H nisoxetine and (3)H WIN 35,428 reveal selective effects of gonadectomy and hormone replacement in adult male rats on norepinephrine but not dopamine transporter sites in the cerebral cortex.

Authors:  B Meyers; M F Kritzer
Journal:  Neuroscience       Date:  2008-12-14       Impact factor: 3.590

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