Literature DB >> 344346

Synergy between sulphonamide and trimethoprim in the presence of pus.

P N Edmunds.   

Abstract

Synergy between sulphadiazine and trimethoprim against Escherichia coli has been demonstrated in culture media not containing lysed horse blood despite the presence of pus or a pus extract which inhibited the action of each drug separately. Synergy may therefore be important where pus is present in vivo.

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Year:  1978        PMID： 344346      PMCID： PMC1145209          DOI： 10.1136/jcp.31.2.162

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  4 in total

1.  Combined antibacterial action in vitro of trimethoprim and sulphonamides. The in vitro nature of synergy.

Authors:  S R Bushby
Journal:  Postgrad Med J       Date:  1969-11       Impact factor: 2.401

2.  Activity and interaction of trimethoprim and sulphamethoxazole against Escherichia coli.

Authors:  D Greenwood; F O'Grady
Journal:  J Clin Pathol       Date:  1976-02       Impact factor: 3.411

3.  Trimethoprim: laboratory and clinical studies.

Authors:  J H Darrell; L P Garrod; P M Waterworth
Journal:  J Clin Pathol       Date:  1968-03       Impact factor: 3.411

4.  A reappraisal of the antibacterial action of cotrimoxazole in vitro.

Authors:  E L Lewis; J D Anderson; R W Lacey
Journal:  J Clin Pathol       Date:  1974-02       Impact factor: 3.411
  4 in total

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