Literature DB >> 34429395

A severe case of non-infective myositis six weeks post intramuscular injections of Onabotulinum toxin A (Botox) in a young man with tetraplegia: case report.

Roxana Edith Heriseanu1, Priyadarshini Chari2.   

Abstract

INTRODUCTION: Myositis of unknown aetiology might be a very rare complication of intramuscular injections of onabotulinum toxin A (Botox) for spasticity treatment. CASE
PRESENTATION: We describe a case of significant myositis of unknown aetiology in a 17-year-old man, who was admitted for rehabilitation 4 months after his initial spinal cord injury (SCI) as a result of a mountain bike accident. He has an incomplete tetraplegia, C4 AIS B international Standards for Neurological Classification for Spinal Cord Injury (ISNCSCI) [1] due to C5 vertebra 3 column fracture [2]. He had severe spasticity of his lower limb muscles treated with Botox, following which, he required two acute hospital transfers for diagnosis and management of myositis. DISCUSSION: This is a severe unusual presentation of myositis caused by intramuscular botulinum toxin for treatment of spasticity, in the frequent setting of spasticity where intramuscular botulinum toxin injections are routinely used.
© 2021. The Author(s), under exclusive licence to International Spinal Cord Society.

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Year:  2021        PMID: 34429395      PMCID: PMC8384850          DOI: 10.1038/s41394-021-00442-1

Source DB:  PubMed          Journal:  Spinal Cord Ser Cases        ISSN: 2058-6124


  11 in total

Review 1.  A systematic review of the Tardieu Scale for the measurement of spasticity.

Authors:  A B Haugh; A D Pandyan; G R Johnson
Journal:  Disabil Rehabil       Date:  2006-08-15       Impact factor: 3.033

2.  What is spasticity?

Authors:  J W Lance
Journal:  Lancet       Date:  1990-03-10       Impact factor: 79.321

3.  Phase 3 Study of OnabotulinumtoxinA Distributed Between Frontalis, Glabellar Complex, and Lateral Canthal Areas for Treatment of Upper Facial Lines.

Authors:  Koenraad De Boulle; William Philip Werschler; Michael H Gold; Suzanne Bruce; Gerhard Sattler; Patricia Ogilvie; James Street; Kristin E Larsen; Irina Yushmanova; Xiaofang Lei; Elisabeth Lee; Domenico Vitarella; Cheri Mao
Journal:  Dermatol Surg       Date:  2018-11       Impact factor: 3.398

4.  Botulinum toxin alleviates dysphagia of patients with inclusion body myositis.

Authors:  Aleksi Schrey; Laura Airas; Manu Jokela; Jaakko Pulkkinen
Journal:  J Neurol Sci       Date:  2017-07-24       Impact factor: 3.181

5.  A randomised, double-blind, dose-ranging study to evaluate efficacy and safety of three doses of botulinum toxin type A (Botox) for the treatment of spastic foot.

Authors:  F Mancini; G Sandrini; A Moglia; G Nappi; C Pacchetti
Journal:  Neurol Sci       Date:  2005-04       Impact factor: 3.307

Review 6.  Diagnosis, pathogenesis and treatment of myositis: recent advances.

Authors:  P-O Carstens; J Schmidt
Journal:  Clin Exp Immunol       Date:  2014-03       Impact factor: 4.330

7.  OnabotulinumtoxinA for the Treatment of Poststroke Distal Lower Limb Spasticity: A Randomized Trial.

Authors:  Theodore Wein; Alberto Esquenazi; Wolfgang H Jost; Anthony B Ward; Grace Pan; Rozalina Dimitrova
Journal:  PM R       Date:  2018-01-09       Impact factor: 2.298

Review 8.  Pathophysiology of spasticity: implications for neurorehabilitation.

Authors:  Carlo Trompetto; Lucio Marinelli; Laura Mori; Elisa Pelosin; Antonio Currà; Luigi Molfetta; Giovanni Abbruzzese
Journal:  Biomed Res Int       Date:  2014-10-30       Impact factor: 3.411

Review 9.  Current Treatment for Myositis.

Authors:  Simone Barsotti; Ingrid E Lundberg
Journal:  Curr Treatm Opt Rheumatol       Date:  2018-09-15
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