| Literature DB >> 34427736 |
Aaron Juche1, Fabian Leo2, Christian Grohé2, Dag Wormanns3, Andreas Krause4.
Abstract
This case report describes the very rare simultaneous occurrence of rheumatoid arthritis and granulomatosis with polyangiitis with the only organ manifestation of life-threatening bilateral pulmonary cavities. Due to the acuteness of the vasculitis, treatment was primarily with cyclophosphamide infusions and high-dose glucocorticoids, and in the further course with high-dose methotrexate. Routine thoracic imaging also seems to be useful when conventional basic rheumatologic treatment is newly initiated, as treatment-decisive changes are seen with a relevant frequency. The occurrence of both autoimmune diseases might be due to common genetic predispositions.Entities:
Keywords: Cavitary lung disease; Differential diagnosis; Granulomatosis with polyangiitis; PR3-ANCA; Rheumatoid arthritis
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Year: 2021 PMID: 34427736 DOI: 10.1007/s00393-021-01064-6
Source DB: PubMed Journal: Z Rheumatol ISSN: 0340-1855 Impact factor: 1.530