| Literature DB >> 34426675 |
Haishui Huang1,2, Xiaoming He3,4,5, Martin L Yarmush6,7.
Abstract
The three classical core technologies for the preservation of live mammalian biospecimens-slow freezing, vitrification and hypothermic storage-limit the biomedical applications of biospecimens. In this Review, we summarize the principles and procedures of these three technologies, highlight how their limitations are being addressed via the combination of microfabrication and nanofabrication, materials science and thermal-fluid engineering and discuss the remaining challenges.Entities:
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Year: 2021 PMID： 34426675 PMCID： PMC8765766 DOI： 10.1038/s41551-021-00784-z
Source DB: PubMed Journal: Nat Biomed Eng ISSN： 2157-846X Impact factor: 29.234