Güler Berkiten1, Defne Gürbüz2, Onur Akan3, Belgin Tutar4, Melis Koşar Tunç2, Semih Karaketir5, Hasan Sami Bircan4, Ertan Berkiten6, Hüseyin Sarı4, Yavuz Atar4, Yavuz Uyar4. 1. Department of Otorhinolaryngology-Head and Neck Surgery, University Health of Sciences Prof. Dr. Cemil Taşçioğlu Training and Research Hospital Hospital, Darulaceze Cad. No: 25 Okmeydani, Sisli/Istanbul, Turkey. gulerberkiten@gmail.com. 2. Department of Radiology, Prof. Dr. Cemil Taşçioğlu Training and Research Hospital Hospital, Darulaceze Cad. No: 25 Okmeydani, Sisli/Istanbul, Turkey. 3. Department of Neurology, Prof. Dr. Cemil Taşçioğlu Training and Research Hospital Hospital, Darulaceze Cad. No: 25 Okmeydani, Sisli/Istanbul, Turkey. 4. Department of Otorhinolaryngology-Head and Neck Surgery, University Health of Sciences Prof. Dr. Cemil Taşçioğlu Training and Research Hospital Hospital, Darulaceze Cad. No: 25 Okmeydani, Sisli/Istanbul, Turkey. 5. Department of Otorhinolaryngology-Head and Neck Surgery, Bulanik State Hospital, Muş, Istanbul, Turkey. 6. Faculty of Medicine, Istanbul University Cerrahpasa, Istanbul, Turkey.
Abstract
STUDY DESIGN: Retrospective cohort. OBJECTIVES: The objective of the study is to evaluate a relationship between idiopathic intracranial hypertension (IIH) and superior semicircular canal dehiscence (SSCD) of bone overlying the superior semicircular canal (SSC). MATERIALS AND METHODS: A total of 57 (114 ears) individuals, 20 of whom were controls and 37 of whom were IIH, were included in the study. Individuals were evaluated with 0.8 mm slice thickness computed tomography (CT) images for SSC bony roof thickness and SSCD. Thickness of the bony roof over the SSC was graded from Grade 1 to Grade 4. Grade 3 was defined as pre-dehiscence and Grade 4 as dehiscence. RESULTS: Bony roof thickness was 1.25 mm in the control group and 0.76 mm in the IIH group. When bony roof thickness was compared between the groups, it was found to be significantly thinner in the IIH group (p = 0.012). In the IIH group, while dehiscence was detected in 25 of 74 ears, no dehiscence was detected in 49 ears. In the control group, while dehiscence was detected in 5 ears, no dehiscence was detected in 35 ears. The difference is statistically significant (p = 0.015). The correlation between bony roof thickness and cerebrospinal fluid (CSF) pressure in the IIH group was not statistically significant (p = 0.343; rho = 0.110). The correlation between bony roof thickness and age in the IIH group was not statistically significant (p = 0.082; rho = - 0.164). CONCLUSION: Increased CSF pressure in patients with IIH may cause chronic, progressive, and irreversible damage to the bone of the SSC and, according to our study, the rate of SSCD was found to be high in IIH patients.
STUDY DESIGN: Retrospective cohort. OBJECTIVES: The objective of the study is to evaluate a relationship between idiopathic intracranial hypertension (IIH) and superior semicircular canal dehiscence (SSCD) of bone overlying the superior semicircular canal (SSC). MATERIALS AND METHODS: A total of 57 (114 ears) individuals, 20 of whom were controls and 37 of whom were IIH, were included in the study. Individuals were evaluated with 0.8 mm slice thickness computed tomography (CT) images for SSC bony roof thickness and SSCD. Thickness of the bony roof over the SSC was graded from Grade 1 to Grade 4. Grade 3 was defined as pre-dehiscence and Grade 4 as dehiscence. RESULTS: Bony roof thickness was 1.25 mm in the control group and 0.76 mm in the IIH group. When bony roof thickness was compared between the groups, it was found to be significantly thinner in the IIH group (p = 0.012). In the IIH group, while dehiscence was detected in 25 of 74 ears, no dehiscence was detected in 49 ears. In the control group, while dehiscence was detected in 5 ears, no dehiscence was detected in 35 ears. The difference is statistically significant (p = 0.015). The correlation between bony roof thickness and cerebrospinal fluid (CSF) pressure in the IIH group was not statistically significant (p = 0.343; rho = 0.110). The correlation between bony roof thickness and age in the IIH group was not statistically significant (p = 0.082; rho = - 0.164). CONCLUSION: Increased CSF pressure in patients with IIH may cause chronic, progressive, and irreversible damage to the bone of the SSC and, according to our study, the rate of SSCD was found to be high in IIH patients.
Authors: Christopher A Schutt; Paul Neubauer; Ravi N Samy; Myles L Pensak; Jeffery J Kuhn; Meir Herschovitch; John F Kveton Journal: Otol Neurotol Date: 2015-03 Impact factor: 2.311