Literature DB >> 34422701

Hepatic tuberculosis: myriad of hues.

Arup Choudhury1, Jayendra Shukla1, Gaurav Mahajan1, Day Krishna Jha1, Pankaj Gupta2, Vishal Sharma3.   

Abstract

INTRODUCTION: Gastrointestinal tuberculosis is an important form of extrapulmonary tuberculosis but liver involvement is uncommon. Hepatic tuberculosis can manifest in variable manners including as a space occupying lesion, diffuse infiltration by granulomas (granulomatous hepatitis) and as liver abscess. Hepatic tuberculosis is usually associated with lesions elsewhere but the diagnosis is often not considered because of rarity. CASE REPORT: We report two cases of hepatic involvement by tuberculosis: one in the form of liver abscess and the other having multiple hypodense hepatic lesions along with peritoneal involvement. The presence of ascites, visceral scalloping and multiple hypodense lesions resulted in a diagnostic confusion with disseminated malignancy but GeneXpert Ultra (Cepheid, USA) helped in making the diagnosis. DISCUSSION: Hepatic tuberculosis should be considered in the differential diagnosis of hepatic space occupying lesions and abscesses. This is especially important in TB endemic regions and in patients where there is involvement of other organs especially the lungs.
CONCLUSIONS: Newer microbiological modalities including GeneXpert Ultra could help in making a diagnosis of hepatic tuberculosis. GERMS.

Entities:  

Keywords:  GeneXpert Ultra; PCR; Tuberculous peritonitis; ascites; gastrointestinal tuberculosis; peritoneal carcinomatosis; pseudomyxoma peritonei

Year:  2021        PMID: 34422701      PMCID: PMC8373414          DOI: 10.18683/germs.2021.1266

Source DB:  PubMed          Journal:  Germs        ISSN: 2248-2997


  9 in total

1.  Imaging diagnosis of 12 patients with hepatic tuberculosis.

Authors:  Ri-Sheng Yu; Shi-Zheng Zhang; Jian-Jun Wu; Rong-Fen Li
Journal:  World J Gastroenterol       Date:  2004-06-01       Impact factor: 5.742

Review 2.  Imaging in discriminating intestinal tuberculosis and Crohn's disease: past, present and the future.

Authors:  Pradeep Goyal; Jimil Shah; Sonali Gupta; Pankaj Gupta; Vishal Sharma
Journal:  Expert Rev Gastroenterol Hepatol       Date:  2019-10-05       Impact factor: 3.869

Review 3.  Granulomas of the liver.

Authors:  Emma L Culver; Jennifer Watkins; Rachel H Westbrook
Journal:  Clin Liver Dis (Hoboken)       Date:  2016-04-27

4.  Visceral scalloping on abdominal computed tomography due to abdominal tuberculosis.

Authors:  Vishal Sharma; Anmol Bhatia; Sarthak Malik; Navjeet Singh; Surinder S Rana
Journal:  Ther Adv Infect Dis       Date:  2017-02-13

5.  Diagnostic accuracy of the Xpert MTB/RIF assay for abdominal tuberculosis: a systematic review and meta-analysis.

Authors:  Vishal Sharma; Hariom Soni; Praveen Kumar-M; Saurabh Dawra; Shubhra Mishra; Harshal S Mandavdhare; Harjeet Singh; Usha Dutta
Journal:  Expert Rev Anti Infect Ther       Date:  2020-09-20       Impact factor: 5.091

Review 6.  A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection.

Authors:  Andrew J Hickey; Lilishia Gounder; Mahomed-Yunus S Moosa; Paul K Drain
Journal:  BMC Infect Dis       Date:  2015-05-06       Impact factor: 3.090

7.  Evaluation of polymerase chain reaction in space-occupying lesions of liver reported as granulomatous inflammation/tuberculosis on fine-needle aspiration cytology.

Authors:  Kusum Sharma; Nalini Gupta; Kapil Goyal; Ajay Kumar Duseja; Aman Sharma; Arvind Rajwanshi
Journal:  Cytojournal       Date:  2017-01-20       Impact factor: 2.091

8.  More on hepatic granulomas.

Authors:  Resat Ozaras; Mucahit Yemisen; Ilker Inanc Balkan
Journal:  Diagn Pathol       Date:  2015-11-19       Impact factor: 2.644

  9 in total

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