| Literature DB >> 34417742 |
Xinna Zhang1,2, George A Calin3,4.
Abstract
Long non-coding RNAs (lncRNAs) are an important class of pervasive genes involved in a variety of biological functions. The abnormal expression of lncRNAs has been implicated in a range of many human diseases, including cancer. To date, a small number of functional lncRNAs have been well characterized. lncRNA expression profiling may help to identify useful molecular biomarkers and targets for novel therapeutic approaches. In this chapter, we describe a highly efficient lncRNA expression profiling method using a custom-designed microarray.Entities:
Keywords: Microarray profiling; cDNA labeling; cDNA synthesis; lncRNA expression
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Year: 2021 PMID： 34417742 DOI： 10.1007/978-1-0716-1697-0_6
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745