| Literature DB >> 34416186 |
Bo Shen1, Gursimran S Kochhar2, Revital Kariv3, Xiuli Liu4, Udayakumar Navaneethan5, David T Rubin6, Raymond K Cross7, Akira Sugita8, André D'Hoore9, Jason Schairer10, Francis A Farraye11, Ravi P Kiran12, Philip Fleshner13, Joel Rosh14, Samir A Shah15, Shannon Chang16, Ellen Scherl17, Darrell S Pardi18, David A Schwartz19, Paulo G Kotze20, David H Bruining18, Sunanda V Kane18, Jessica Philpott21, Bincy Abraham22, Jonathan Segal23, Rocio Sedano24, Maia Kayal25, Stuart Bentley-Hibbert26, Dino Tarabar27, Sandra El-Hachem2, Priya Sehgal28, James T McCormick29, Joseph A Picoraro30, Mark S Silverberg31, Charles N Bernstein32, William J Sandborn33, Séverine Vermeire34.
Abstract
Restorative proctocolectomy with ileal pouch-anal anastomosis is an option for most patients with ulcerative colitis or familial adenomatous polyposis who require colectomy. Although the construction of an ileal pouch substantially improves patients' health-related quality of life, the surgery is, directly or indirectly, associated with various structural, inflammatory, and functional adverse sequelae. Furthermore, the surgical procedure does not completely abolish the risk for neoplasia. Patients with ileal pouches often present with extraintestinal, systemic inflammatory conditions. The International Ileal Pouch Consortium was established to create this consensus document on the diagnosis and classification of ileal pouch disorders using available evidence and the panellists' expertise. In a given individual, the condition of the pouch can change over time. Therefore, close monitoring of the activity and progression of the disease is essential to make accurate modifications in the diagnosis and classification in a timely manner.Entities:
Mesh:
Year: 2021 PMID: 34416186 DOI: 10.1016/S2468-1253(21)00101-1
Source DB: PubMed Journal: Lancet Gastroenterol Hepatol