Literature DB >> 344128

Immunoelectron cytochemical localization of motilin in human duodenal enterochromaffin cells.

P U Heitz, M Kasper, G Krey, J M Polak, A G Pearse.   

Abstract

Two types of enterochromaffin cells can be demonstrated in the human duodenal mucosa by means of the Masson-Fontana reaction for argentaffinity applied to ultrathin sections. The 22-amino acid peptide motilin has now been localized exclusively to the duodenal type of enterochromaffin cell by immunoelectron microscopy. This cell occurs predominantly in the duodenum and upper jejunum. It is concluded that at least two types of enterochromaffin cells exist in the human gut mucosa and that they produce at least one biogenic amine as well as two peptides. Therefore they could provide a useful model for studies of the interrelationship of storage and release of amines and peptides.

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Year:  1978        PMID: 344128

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


  10 in total

1.  Substance P in the argentaffin carcinoid of the caecum: biochemical and biological characterization.

Authors:  M Ratzenhofer; R Gamse; H Höfler; L Auböck; H Popper; P Pohl; F Lembeck
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1981

Review 2.  Gut endocrine and neural peptides.

Authors:  Anne E Bishop; Julia M Polak
Journal:  Endocr Pathol       Date:  1990-03       Impact factor: 3.943

3.  Ultrastructure of enterochromaffin cells and associated neural and vascular elements in the mouse duodenum.

Authors:  P R Wade; J A Westfall
Journal:  Cell Tissue Res       Date:  1985       Impact factor: 5.249

4.  5-Hydroxytryptamine and cholera secretion: a histochemical and physiological study in cats.

Authors:  O Nilsson; J Cassuto; P A Larsson; M Jodal; P Lidberg; H Ahlman; A Dahlström; O Lundgren
Journal:  Gut       Date:  1983-06       Impact factor: 23.059

5.  Enteropathy of coeliac disease in adults: increased number of enterochromaffin cells the duodenal mucosa.

Authors:  K Sjölund; J Alumets; N O Berg; R Håkanson; F Sundler
Journal:  Gut       Date:  1982-01       Impact factor: 23.059

6.  Gastro-intestinal and neurohormonal peptides in the alimentary tract and cerebral complex of Ciona intestinalis (Ascidiaceae).

Authors:  H A Fritsch; S Van Noorden; A G Pearse
Journal:  Cell Tissue Res       Date:  1982       Impact factor: 5.249

7.  Ultrastructural localization of motilin in endocrine cells of human and dog intestine by the immunogold technique.

Authors:  L Usellini; A M Buchan; J M Polak; C Capella; M Cornaggia; E Solcia
Journal:  Histochemistry       Date:  1984

8.  Immunocytological evidence of motilin- and secretin-containing cells in the human fetal gastro-entero-pancreatic system.

Authors:  P Leduque; C Paulin; J A Chayvialle; P M Dubois
Journal:  Cell Tissue Res       Date:  1981       Impact factor: 5.249

9.  Immunocytochemical identification and localization of peptide hormones in the gastro-entero-pancreatic (GEP) endocrine system of the mouse and a stomachless fish, Barbus conchonius.

Authors:  J H Rombout; C P van der Grinten; F M Binkhorst; J J Taverne-Thiele; H Schooneveld
Journal:  Histochemistry       Date:  1986

10.  Differential expression of motilin receptor in various parts of gastrointestinal tract in dogs.

Authors:  Yu He; Hui Wang; DongYan Yang; ChengYan Wang; LanLan Yang; Chunxiang Jin
Journal:  Gastroenterol Res Pract       Date:  2015-03-31       Impact factor: 2.260

  10 in total

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