Literature DB >> 34410749

Personalizing interventions using real-world interactions: Improving symptoms and social functioning in schizophrenia with tailored metacognitive therapy.

Kyle S Minor1, Matthew P Marggraf1, Beshaun J Davis1, Jessica L Mickens1, Danielle B Abel1, Megan L Robbins1, Kelly D Buck2, Sarah E Wiehe3, Paul H Lysaker2.   

Abstract

OBJECTIVE: When clients' lives are not reflected in therapy, they struggle to apply the skills learned in treatment to everyday situations. In this pilot study, we determined if using clients' real-world interactions in therapy could effectively target metacognitive capacity-yielding improved symptoms and social functioning-by tailoring treatment to focus on issues faced by clients in daily life.
METHOD: Using a randomized controlled trial design, schizophrenia subjects with metacognitive deficits completed 24 sessions of: (a) Standard Metacognitive Reflection and Insight Therapy (MERIT); or (b) Tailored MERIT. Real-world interactions were captured via the Electronically Activated Recorder (EAR), a smartphone application that passively records audio in daily life. All subjects wore the EAR; however, real-world interactions were only used to personalize sessions in Tailored MERIT.
RESULTS: Feasibility and acceptability were shown; those in Tailored MERIT wore the EAR 84% of their waking hours and reported minimal burden. When compared to Standard MERIT, Tailored MERIT participants showed large pre-post reductions in negative metacognitive beliefs and disorganized symptoms. Small, but nonsignificant, improvements in social functioning were also observed.
CONCLUSIONS: Compared to an evidence-based benchmark, we observed that real-world interactions can be used to tailor metacognitive therapy and improve outcomes in schizophrenia. Tailored MERIT has the potential to impact practice by personalizing treatment to account for individual variations in environment and lifestyle-aligning with the Precision Medicine Initiative-in a way that is not possible with current therapy. This is particularly salient in schizophrenia, where limited insight and cognitive deficits often make subjective reporting unreliable. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

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Year:  2021        PMID: 34410749      PMCID: PMC8857308          DOI: 10.1037/ccp0000672

Source DB:  PubMed          Journal:  J Consult Clin Psychol        ISSN: 0022-006X


  47 in total

1.  Characteristics of schizophrenia suicides compared with suicides by other diagnosed psychiatric disorders and those without a psychiatric disorder.

Authors:  Juncheng Lyu; Jie Zhang
Journal:  Schizophr Res       Date:  2014-03-20       Impact factor: 4.939

2.  The Electronically Activated Recorder (EAR): a device for sampling naturalistic daily activities and conversations.

Authors:  M R Mehl; J W Pennebaker; D M Crow; J Dabbs; J H Price
Journal:  Behav Res Methods Instrum Comput       Date:  2001-11

3.  Social functioning in schizotypy: How affect influences social behavior in daily life.

Authors:  Kyle S Minor; Kathryn L Hardin; Danielle M Beaudette; Lesley C Waters; Anna L White; Virgilio Gonzenbach; Megan L Robbins
Journal:  J Clin Psychol       Date:  2020-07-02

4.  Naturalistically observed swearing, emotional support, and depressive symptoms in women coping with illness.

Authors:  Megan L Robbins; Elizabeth S Focella; Shelley Kasle; Ana María López; Karen L Weihs; Matthias R Mehl
Journal:  Health Psychol       Date:  2011-05-16       Impact factor: 4.267

5.  The "Right Stuff" Revisited: What Have We Learned About the Determinants of Daily Functioning in Schizophrenia?

Authors:  Michael F Green; Katiah Llerena; Robert S Kern
Journal:  Schizophr Bull       Date:  2015-03-07       Impact factor: 9.306

6.  Conceptual disorganization weakens links in cognitive pathways: Disentangling neurocognition, social cognition, and metacognition in schizophrenia.

Authors:  Kyle S Minor; Matthew P Marggraf; Beshaun J Davis; Lauren Luther; Jenifer L Vohs; Kelly D Buck; Paul H Lysaker
Journal:  Schizophr Res       Date:  2015-10-05       Impact factor: 4.939

7.  Naturalistic observation of health-relevant social processes: the electronically activated recorder methodology in psychosomatics.

Authors:  Matthias R Mehl; Megan L Robbins; Fenne Große Deters
Journal:  Psychosom Med       Date:  2012-05       Impact factor: 4.312

8.  Quality versus quantity: Determining real-world social functioning deficits in schizophrenia.

Authors:  Danielle B Abel; Michelle P Salyers; Wei Wu; Mahogany A Monette; Kyle S Minor
Journal:  Psychiatry Res       Date:  2021-05-01       Impact factor: 11.225

Review 9.  Metacognitive function and fragmentation in schizophrenia: Relationship to cognition, self-experience and developing treatments.

Authors:  Paul H Lysaker; Kyle S Minor; John T Lysaker; Ilanit Hasson-Ohayon; Kelsey Bonfils; Jesse Hochheiser; Jenifer L Vohs
Journal:  Schizophr Res Cogn       Date:  2019-04-24

Review 10.  Metacognitive Reflection and Insight Therapy: A Recovery-Oriented Treatment Approach for Psychosis.

Authors:  Paul H Lysaker; Emily Gagen; Reid Klion; Aieyat Zalzala; Jenifer Vohs; Laura A Faith; Bethany Leonhardt; Jay Hamm; Ilanit Hasson-Ohayon
Journal:  Psychol Res Behav Manag       Date:  2020-04-02
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