Literature DB >> 34409576

Can anatomical feasibility studies drive neurosurgical procedures and reach patients faster than traditional translational research?

Joe Iwanaga1,2,3, Nicole A Boggio4, C J Bui5, Aaron S Dumont4, R Shane Tubbs4,6,5,7,8,9.   

Abstract

Often, surgical techniques are practiced and studied in the anatomy laboratory. Occasionally, new surgical methods are developed with cadaveric anatomical studies. Some cadaveric feasibility studies, if published, might go on to be used by surgeons from around the world for improved patient care. Herein, we review our experience with 37 published anatomical feasibility studies over an 18-year period (2002-2020) and analyze the literature for published examples of surgical application of these same anatomical studies. We found that, for cadaveric anatomical feasibility studies within 7 years of their publication date, approximately 22% will be used in neurosurgery with the clinical applications published. Of these studies awarded clinical citation within 7 years of publication, the median time to that citation was approximately 3.4 years. As the average time for translational research to reach patient care is 17 years, cadaveric anatomical studies in this series reached patient care much sooner than traditional translational research. Cadaveric anatomical studies, based on our experience, can drive neurosurgical procedures.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Anatomy; Cadaver; Feasibility studies; Patient care; Publications; Surgical procedures; Translational research

Mesh:

Year:  2021        PMID: 34409576     DOI: 10.1007/s10143-021-01626-x

Source DB:  PubMed          Journal:  Neurosurg Rev        ISSN: 0344-5607            Impact factor:   2.800


  49 in total

1.  Approach to the cervical portion of the vagus nerve via the posterior cervical triangle: a cadaveric feasibility study with potential use in vagus nerve stimulation procedures.

Authors:  R Shane Tubbs; Marios Loukas; Mohammadali M Shoja; E George Salter; W Jerry Oakes; Jeffrey P Blount
Journal:  J Neurosurg Spine       Date:  2006-12

2.  Practice-based research--"Blue Highways" on the NIH roadmap.

Authors:  John M Westfall; James Mold; Lyle Fagnan
Journal:  JAMA       Date:  2007-01-24       Impact factor: 56.272

3.  Intra-abdominal laparoscopic pudendal canal decompression - a feasibility study.

Authors:  Marios Loukas; Robert G Louis; R Shane Tubbs; Christopher Wartmann; Gene L Colborn
Journal:  Surg Endosc       Date:  2007-11-20       Impact factor: 4.584

4.  Phrenic nerve neurotization utilizing the spinal accessory nerve: technical note with potential application in patients with high cervical quadriplegia.

Authors:  R Shane Tubbs; Blake Pearson; Marios Loukas; Ghaffar Shokouhi; Mohammadali M Shoja; W Jerry Oakes
Journal:  Childs Nerv Syst       Date:  2008-06-07       Impact factor: 1.475

5.  Internal Thoracic Artery to Middle Cerebral Artery Bypass Surgery: Cadaveric Feasibsility Study.

Authors:  Stephen Monteith; Oded Goren; Ragu Sampath; Eric Lehr; Akshal Patel; Paul J Choi; Joe Iwanaga; Marios Loukas; R Shane Tubbs
Journal:  World Neurosurg       Date:  2018-01-12       Impact factor: 2.104

6.  Contralateral spinal accessory nerve for ipsilateral neurotization of branches of the brachial plexus: a cadaveric feasibility study.

Authors:  R Shane Tubbs; Martin M Mortazavi; Mohammadali M Shoja; Marios Loukas; Aaron A Cohen-Gadol
Journal:  J Neurosurg       Date:  2011-03-04       Impact factor: 5.115

7.  A novel method for cerebrospinal fluid diversion: a cadaveric and animal study.

Authors:  R Shane Tubbs; David Bauer; M Renee Chambers; Marios Loukas; Mohammadali M Shoja; Aaron A Cohen-Gadol
Journal:  Neurosurgery       Date:  2011-02       Impact factor: 4.654

8.  Use of autologous scapula for cranioplasty: cadaveric feasibility study.

Authors:  R Shane Tubbs; Marios Loukas; Mohammadali M Shoja; Frank Salter; E George Salter; W Jerry Oakes
Journal:  Childs Nerv Syst       Date:  2008-02-26       Impact factor: 1.475

9.  Diffusion theory and knowledge dissemination, utilization and integration.

Authors:  Lawrence W Green; Judith M Ottoson; César García; Robert A Hiatt; Maria L Roditis
Journal:  Front Public Health Serv Syst Res       Date:  2014

Review 10.  The answer is 17 years, what is the question: understanding time lags in translational research.

Authors:  Zoë Slote Morris; Steven Wooding; Jonathan Grant
Journal:  J R Soc Med       Date:  2011-12       Impact factor: 5.344

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